中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (3): 535-538.doi: 10.3969/j.issn.1673-8225.2011.03.038

• 生物材料学术探讨 biomaterial academic discussion • 上一篇    下一篇

组织工程生物绷带及敷料在创伤修复领域中的应用

刘  静   

  1. 徐州师范大学体育学院，江苏省徐州市  221116
  • 收稿日期:2010-11-04 修回日期:2010-12-04 出版日期:2011-01-15 发布日期:2011-01-15
  • 作者简介:刘静★，女，1977年生，江苏省徐州市人，汉族，2010年北京体育大学毕业，硕士，主要从事体育保健与教学方面的研究。 hr1128@126.com
  • 基金资助:

    国家社会科学基金项目(10BTY028)。

Application of biological bandage and dressing in wound healing

Liu Jing   

  1. Institute of Physical Education, Xuzhou Normal University, Xuzhou  221116, Jiangsu Province, China
  • Received:2010-11-04 Revised:2010-12-04 Online:2011-01-15 Published:2011-01-15
  • About author:Liu Jing★, Master, Institute of Physical Education, Xuzhou Normal University, Xuzhou 221116, Jiangsu Province, China hr1128@126.com
  • Supported by:

    the National Social Science Foundation of China, No.103TY028*

PDF

713

被引次数

14

摘要：

背景：医用敷料作为伤口处的覆盖物，在伤口愈合过程中，可以替代受损的皮肤起到暂时性屏障作用，避免或控制伤口感染，提供有利于创面愈合的环境。如何既能快速固定、有效止血，又可以减轻或避免止血后对伤肢血循环造成的不利影响，加快伤口愈合、减轻伤痛是创伤急救医学亟待解决的难题。
目的：文章综述了医用生物敷料在创伤修复领域中的应用现状及研究进展，揭示其发展前景，为其在创伤修复过程中的应用提供理论基础。
方法：应用计算机检索CNKI和PubMed数据库中1998-01/2008-12关于医用生物敷料的文章，在标题和摘要中以“医用敷料；生物材料，壳聚糖，水凝胶，组织工程”或“medical dressing，chitosan”为检索词进行检索。选择文章内容与创伤修复相关，同一领域文献则选择近期发表或发表在权威杂志文章。初检得到146篇文献，中文107篇，英文39篇，根据纳入标准选择38篇文章进行综述。
结果与结论：就目前临床使用及研究的医用敷料，根据其所用的材料将其分成了天然材料和合成高分子，无机材料和复合材料，并对敷料类产品质量控制中出现的问题进行了讨论，展望了敷料类产品的未来发展方向。为医用敷料类产品的研发提供理论依据。

关键词: 医用敷料, 生物材料, 组织工程, 壳聚糖, 水凝胶

Abstract:

BACKGROUND: Medical dressings as covering of the wound can replace damaged skin and play a temporary barrier function in the process of wound healing, and avoid or control wound infection to provide a conductive environment for wound healing. How to fixed quickly, stop bleeding effectively, and reduce or prevent the adverse effect of injured limb blood circulation after hemostasis, the acceleration of wound healing and the reduction of pain is an urgent problem of trauma critical care medicine.
OBJECTIVE: To introduce the application status and research progress of medical biological dressings in the field of wound healing, and reveal its development prospect to provide theoretical basis for the application of medical biological dressings in the progress of wound healing.
METHODS: The articles concerning medical biological dressings were retrieved in CNKI database and PubMed database from January 1998 to December 2008, using the key words of “medical dressing, biological material, chitosan, hydrogel, tissue engineering” in Chinese or “medical dressing, biological material, chitosan, hydrogel, tissue engineering” in English in the title and abstract. The content of articles related with wound healing and literatures recently published or published in authoritative magazines from the same field were selected. Totally 146 literatures were primarily selected (Chinese 107, English 39), according to inclusion criteria, 38 documents of which were involved for summarization.
RESULTS AND CONCLUSION: The medical dressings of the current clinical use and research were divided into natural material and synthetic macromolecule, inorganic material and composite according to the materials. Moreover, the problems of dressing products in the quality control were discussed, the further direction of dressing products was prospected, and a theoretical basis for research and development of dressing products were provided.

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