中国组织工程研究

中国组织工程研究

• 骨与关节生物力学 bone and joint biomechanics • 上一篇    下一篇

生物力学测量系统测量软骨损伤后滑膜关节的摩擦性能

牟怡平1，Otto Muller2○，Nicolas Wullker2○   

  1. 1沈阳医学院奉天医院，辽宁省沈阳市  110024
    2图宾根大学，巴登-符腾堡州图宾根市  72076，德国
  • 收稿日期:2013-04-27 修回日期:2013-05-30 出版日期:2013-06-25 发布日期:2013-06-25
  • 通讯作者: Nicolas Wullker，博士，教授，图宾根大学，巴登-符腾堡州图宾根市 72076，德国 NicolasWullker@live.com
  • 作者简介:牟怡平☆，男，1979年生，辽宁省普兰店市人，汉族，2011年德国图宾根大学毕业，博士，主治医师，主要从事骨关节与显微外科研究。 yiping.mu@163.com

Biomechanical measurement system for measuring frictional properties of synovial joint after cartilage injury

Mu Yi-ping1, Otto Muller2, Nicolas Wullker2   

  1. 1 Feng Tian Hospital Affiliated to Shenyang Medical College, Shenyang  110024, Liaoning Province, China
    2 Tuebingen University, Baden-Wuerttemberg Tuebingen  72076, Germany
  • Received:2013-04-27 Revised:2013-05-30 Online:2013-06-25 Published:2013-06-25
  • Contact: Nicolas Wullker, Doctor, Professor, Tuebingen University, Baden-Wuerttemberg Tuebingen 72076, Germany NicolasWullker@live.com
  • About author:Mu Yi-ping☆, Doctor, Attending physician, Feng Tian Hospital　Affiliated to Shenyang Medical College, Shenyang 110024, Liaoning Province, China yiping.mu@163.com

PDF

550

被引次数

1

摘要：

背景：骨性关节炎会导致关节摩擦因数及性能的改变，目前尚没有一种方法能够全面客观的评价及测量关节的摩擦性能。
目的：应用生物力学测量系统观察不同压力条件下关节摩擦性能的变化，及软骨缺损出现时关节摩擦因数的变化。
方法：将羊腕关节固定在生物力学测量系统上，以垂直关节面方向给关节施加100，200，400，800 N的压力，左右5°旋转关节测出平均旋转扭矩及关节摩擦因数。然后在关节面上制作面积为16 mm2的软骨缺损区，测试在100，200，400，800 N压力下的平均扭矩及关节摩擦因数。
结果与结论：当无软骨缺损时，羊腕关节在4种压力状态下的旋转扭矩大小分别为：0.021 7，0.031 7，0.063 0，0.145 0 N•m，关节摩擦因数(μ)分别为：0.006 7，0.007 3，0.012 0和0.014 5；而在软骨缺损时，4种压力状态下的旋转扭矩大小分别为：0.027 0，0.041 7，0.080 6，0.172 4 N•m，关节摩擦因数(μ)分别为：0.008 6，0.009 7，0.013 7和0.016 4。可见，随着压力的增加，旋转扭矩和关节摩擦因数逐渐增大(P < 0.05)，且关节软骨缺损会导致关节旋转扭矩和关节摩擦因数的增大(P < 0.05)。同时关节旋转扭矩与关节摩擦因数明显正相关。

关键词: 骨关节植入物, 骨与关节生物力学, 关节摩擦学, 摩擦因数, 骨性关节炎, 软骨缺损, 生物力学测量系统, 关节压力, 扭矩, 关节软骨退变性疾病, 滑膜

Abstract:

BACKGROUND: Osteoarthritis will change the frictional factor and performance of synovial joints. There is no perfect system to objectively measure and evaluate the fractional properties of synovial joints.
OBJECTIVE: To observe the changes of fractional properties of synovial joints under different pressure conditions with biomechanical measurement system.
METHODS: A sheep’s wrist joint was fixed in the biomechanical measurement system to measure the friction properties. Each sample was tested in four different axial loading conditions: 100 N, 200 N, 400 N and 800 N axial forces that vertical to the joint articular surface, in order to measure the torque and the coefficient by whirligig the joint for 5°. After measurement, 16 mm2 cartilage defects were made in each specimen. Then the torque and the coefficient were measured under 100 N, 200 N, 400 N and 800 N axial forces.
RESULTS AND CONCLUSION: The torque of sheep wrist joint was 0.021 7, 0.031 7, 0.063 0 and 0.145 0 N•m respectively, and the coefficient of fraction was 0.006 7, 0.007 3, 0.012 0 and 0.014 5 μ when it was loaded by four different axial forces without cartilage defect. The torque of sheep wrist joint was 0.027 0, 0.041 7, 0.080 6 and 0.172 4 N•m respectively, and the coefficient of fraction was 0.008 6, 0.009 7, 0.013 7 and 0.016 4 μ when it was loaded by four different axial forces with cartilage defect. The torque and the coefficient of fraction were gradually increased with the increasing of loading forces (P < 0.05), and the articular cartilage defects may lead to the increasing of joint torque and the coefficient of fraction (P < 0.05). The joint torque was positively correlated with coefficient of fraction.

Key words: bone and joint implants, bone and joint biomechanics, joint tribology, friction factor, osteoarthritis, cartilage defects, biomechanical measurement system, joint pressure, torque, articular cartilage degenerative diseases, synovial

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