中国组织工程研究 ›› 2015, Vol. 19 ›› Issue (42): 6808-6812.doi: 10.3969/j.issn.2095-4344.2015.42.016

• 组织构建与生物力学 tissue construction and biomechanics • 上一篇    下一篇

围绝经期妇女体成分及静息能量代谢变化

刘玉兰,阮祥燕,武红琴   

  1. 首都医科大学附属北京妇产医院内分泌科,北京市 100026
  • 出版日期:2015-10-08 发布日期:2015-10-08
  • 通讯作者: 阮祥燕,博士,主任医师,首都医科大学附属北京妇产医院内分泌科,北京市 100026
  • 作者简介:刘玉兰,女,1998年包头医学院毕业,主管护师,主要从事妇科内分泌研究。
  • 基金资助:

    北京市卫生系统高层次卫生技术人才(学科带头人)(2014-2-016);首都医科大学附属北京妇产医院,北京妇幼保健院学科带头人项目(2013-1);国家外国专家局2015年度北京市引进国外技术、管理人才项目(GDJ20151100013)

Body composition and resting energy expenditure in perimenopausal women

Liu Yu-lan, Ruan Xiang-yan, Wu Hong-qin   

  1. Department of Gynecological Endocrinology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China
  • Online:2015-10-08 Published:2015-10-08
  • Contact: Ruan Xiang-yan, M.D., Chief physician, Department of Gynecological Endocrinology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China
  • About author:Liu Yu-lan, Nurse in charge, Department of Gynecological Endocrinology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China
  • Supported by:

    Beijing Municipality Health Technology High-level Talents, No. 2014-2-016; the Discipline Leader Project of Beijing Obstetrics and Gynecology Hospital & Beijing Maternal and Child Health Care Hospital, No. 2013-1; the Foreign Technical and Administrative Talent Introduction Project in 2015, State Administration of Foreign Experts Affairs, China, No. GDJ20151100013

摘要:

背景:女性绝经后雌激素水平下降、年龄增长、活动水平下降都可能引起静息能量消耗的降低,进而引起绝经后女性体成分变化,导致疾病,如肥胖、骨折。
目的:观察绝经前、围绝经期、绝经后妇女体成分及静息代谢率的变化。
方法:收集门诊就诊的2 312例妇女,其中绝经前1 310例、围绝经期790例、绝经后212例,测定体成分和静息能量消耗。
结果与结论:①围绝经期和绝经后女性的全身脂肪百分比显著高于绝经前女性。②3组间的静息代谢率无显著差异,经体质量校正后围绝经期女性的每千克体质量静息代谢率显著低于绝经前女性。③绝经后女性的骨密度、股骨颈抗骨折能力、下肢最大肌力、下肢肌肉分布系数显著低于围绝经期女性和绝经前女性(P < 0.05)。④体质量、下肢肌肉分布系数与每千克体质量静息代谢率呈正相关,身高、体质量指数、全身脂肪含量与每千克体质量静息代谢率呈负相关。以上结果表明,绝经后女性体成分发生变化,身体脂肪含量增加,肌肉含量减少,骨量减少;骨骼、肌肉、关节功能处于退行性变;体成分改变与静息能量消耗之间存在一定的相互关系。
中国组织工程研究杂志出版内容重点:组织构建;骨细胞;软骨细胞;细胞培养;成纤维细胞;血管内皮细胞;骨质疏松组织工程

关键词: 组织构建, 组织工程, 绝经后, 围绝经期, 绝经前, 静息能量消耗, 体成分, 全身脂肪含量, 骨密度

Abstract:

BACKGROUND: Aging, lack of estrogen and few activities may lead to the decrease of resting energy expenditure in menopause women so as to induce the body composition changes, which can result in disease, such as obesity and fracture.

OBJECTIVE: To explore the change of body composition and resting metabolic rate among premenopausal, perimenopausal and postmenopausal women.
METHODS: 2 312 women who came to outpatient clinic were recruited, including 1 310 premenopausal women, 790 perimenopausal women and 212 postmenopausal women. Body composition and resting energy expenditure were measured in each woman.
RESULTS AND CONCLUSION: (1) Body fat percentage of perimenopausal and postmenopausal women was significantly higher than that of pre-menopausal women. (2) There was no significant difference in resting metabolic rate among the three groups. When adjusted body weight, the resting energy expenditure per kilogram was significantly lower in perimenopausal women than in premenopausal women. (3) Bone mineral density, femoral neck strength, lower limb maximal strength, and leg muscle distribution coefficient were significantly lower in postmenopausal women than in perimenopausal and premenopausal women (P < 0.05). (4) Weight and leg muscle distribution coefficient were positively correlated with the resting energy expenditure per kilogram, and height, body mass index, body fat percentage were negatively correlated with the resting energy expenditure per kilogram. These findings indicate that the body composition can change in women after menopause, such as body fat increasing, muscle content decreasing, and bone mass loss. There is a certain relationship between the change in body composition and resting energy expenditure.
中国组织工程研究杂志出版内容重点:组织构建;骨细胞;软骨细胞;细胞培养;成纤维细胞;血管内皮细胞;骨质疏松组织工程

Key words: Postmenopause, Perimenopause, Body Composition, Bone Density