中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (51): 9557-9560.doi: 10.3969/j.issn.1673-8225.2011.51.014

• 纳米生物材料 nanobiomaterials • 上一篇    下一篇

LZB-GC纳米载银抗菌剂在藻酸盐印模材料中的抗菌性

柳文娟1，王  毅2，赵红梅3，刘  斌1，韩  俭1，周  伟1，王  猛1   

  1. 1兰州大学口腔医学院、病原生物学研究所，甘肃省兰州市 730000
    2烟台山人民医院，山东省烟台市 264001
    3兰州市口腔医院，甘肃省兰州市 730000
  • 收稿日期:2011-05-13 修回日期:2011-06-21 出版日期:2011-12-17 发布日期:2011-12-17
  • 通讯作者: 刘斌，博士，教授，硕士生导师，兰州大学口腔医学院，甘肃省兰州市730000 liubkq@ lzu.edu.cn 并列通讯作者：韩俭, 在读博士，副教授，硕士生导师，兰州大学病原生物学研究所，甘肃省兰州市 730000 hanj@lzu.edu.cn
  • 作者简介:柳文娟★，女，1977年生，甘肃省兰州市人，汉族，2004年武汉大学口腔医学院毕业，硕士，讲师，主要从事口腔修复学教学、临床和科研工作。 klys2003@ yahoo.com.cn
  • 基金资助:

    兰州大学中央高校基本科研业务费专项资金资助项目(lzujbky-2010-195)；兰州市科技局科技计划项目(2008-1-86)；甘肃省科技计划项目资助(1107RJYA002)。

Antibacterial properties of LZB-GC nano-silver-filled antibacterial agents used in alginate impression materials

Liu Wen-juan1, Wang Yi2, Zhao Hong-mei3, Liu Bin1, Han Jian1, Zhou Wei1, Wang Meng1   

  1. 1College of Stomatology, Institute of Pathogen Biology, Lanzhou University, Lanzhou  730000, Gansu Province, China
    2Yantanshan Hospital, Yantan  264001, Shandong Province, China
    3Dental Hospital of Lanzhou City, Lanzhou  730000, Gansu Province, China
  • Received:2011-05-13 Revised:2011-06-21 Online:2011-12-17 Published:2011-12-17
  • Contact: Liu Bin, Doctor, Professor, Master’s supervisor, College of Stomatology, Institute of Pathogen Biology, Lanzhou University, Lanzhou 730000, Gansu Province, China liubkq@lzu.edu.cn Correspondence to: Han Jian, Studying for doctorate, Associate professor, Master’s supervisor, College of Stomatology, Institute of Pathogen Biology, Lanzhou University, Lanzhou 730000, Gansu Province, China hanj@lzu.edu.cn
  • About author:Liu Wen-juan★, Master, Lecturer, College of Stomatology, Institute of Pathogen Biology, Lanzhou University, Lanzhou 730000, Gansu Province, China klys2003@ yahoo.com.cn
  • Supported by:

    the Fundamental Research Funds for the Central Universities of Lanzhou University, No. lzujbky-2010-195*; the Plan of Lanzhou Science and Technology Bureau, No. 2008-1-86*; the Science and Technology Program of Gansu Province, No. 1107RJYA002*

PDF

362

被引次数

9

摘要：

背景：关于藻酸盐印模材料的消毒方法一直存在争议。
目的：分析LZB-GC纳米载银抗菌剂在藻酸盐印模材料中的最佳添加比例。
方法：将LZB-GC抗菌剂分别以0.125%，0.25%，0.5%，1%，1.5%，2%，2.5%的比例添加到藻酸盐印模材料中，以未添加LZB-GC抗菌剂的藻酸盐印模材料为对照，采用薄膜密着法测试其对金黄色葡萄球菌和大肠杆菌的抗菌性能。
结果与结论：随着LZB-GC抗菌剂添加量的增加，对金黄色葡萄球菌和大肠杆菌的抗菌率随之增大(P < 0.05)，当添加量达到0.5%及以上，抗菌率可达到99%以上。说明LZB-GC抗菌剂在藻酸盐印模材料中的最佳添加比例为0.5%。

关键词: 抗菌剂, 藻酸盐, 印模材料, 抗菌率, 消毒

Abstract:

BACKGROUND: The disinfection method of alginates impression materials has been controversial.   
OBJECTIVE: To analyze the appropriate ratio of the LZB-GC nano-silver-filled antibacterial agent to the alginate impression material.
METHODS: The LZB-GC antibacterial agents were added into the alginate impression materials according to different contents, including 0.125, 0.25%, 0.5%, 1%, 1.5%, 2% and 2.5%. The alginate impression materials without the LZB-GC antibacterial agents served as a control. Their antibacterial activities were tested by film adhesion method, including Staphylococcus aureus and Escherichia coli.
RESULTS AND CONCLUSION: The antibacterial efficiency was increased as the adding ratios of antibacterial agent against two tested bacteria strains increased (P < 0.05). The antibacterial efficiency was beyond 99% when the adding ratio of antibacterial agent was 0.5% or beyond 0.5%. It was indicated that the best adding ratio of the LZB-GC antibacterial agent in the alginate impression material was 0.5%.

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