中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (4): 753-756.doi: 10.3969/j.issn.1673-8225.2011.04.045

• 骨与关节综述 bone and joint review • 上一篇    下一篇

CT肺功能成像与其临床应用

韩晓雨,葛  莹,李智勇   

  1. 大连医科大学附属第一医院放射科,辽宁省大连市   116011
  • 收稿日期:2010-09-17 修回日期:2010-12-02 出版日期:2011-01-22 发布日期:2011-01-22
  • 通讯作者: 李智勇,硕士,副教授,大连医科大学附属第一医院放射科,辽宁省大连市 116011 zjy_lzy@126. com
  • 作者简介:韩晓雨★,女,1984年,辽宁省辽中县人,汉族,大连医科大学在读硕士,主要从事呼吸系统疾病影像学诊断方面的研究。 hanyu1215@ yahoo.cn

CT pulmonary function imaging and its clinical application

Han Xiao-yu, Ge Ying, Li Zhi-yong   

  1. Department of Radiology, First Hospital of Dalian Medical University, Dalian  116011, Liaoning Province, China
  • Received:2010-09-17 Revised:2010-12-02 Online:2011-01-22 Published:2011-01-22
  • Contact: Li Zhi-yong, Master, Associate professor, Department of Radiology, First Hospital of Dalian Medical University, Dalian 116011, Liaoning Province, China zjy_lzy@126.com
  • About author:Han Xiao-yu★, Studying for master’s degree, Department of Radiology, First Hospital of Dalian Medical University, Dalian 116011, Liaoning Province, China hanyu1215@yahoo. cn

摘要:

背景:随着CT技术及计算机软件的发展,CT不仅能够显示肺部的解剖结构,而且还能够测定肺功能状况,为肺功能的评估与研究提供了一个新方法。
目的:总结CT肺功能成像的分析指标及临床应用,以便将其广泛应用于临床,早期发现及监测呼吸系统疾病。
方法:应用计算机检索CNKI、PubMed数据库中1989-01/2010-05关于CT肺功能的文章,在标题和摘要中以“CT肺功能”或“computed tomography pulmonary function;quantitative CT”为检索词进行检索。选择文章内容与CT肺功能成像与其临床应用有关,同一领域文献则选择近期发表或发表在的权威杂志文章。初检得到中文文献26篇,英文文献287篇,根据纳入标准选择20篇文章进行综述。
结果与结论:肺功能的CT成像研究主要是通过肺容积、密度或象素指数的改变来反映肺组织的功能变化,以揭示肺组织的病理解剖学和病理生理学信息,以期早期发现和早期监测呼吸疾病。CT肺功能的测定在肺气肿、慢阻肺等的定量分析、肺癌及单侧肺移植后肺功能的预测等方面有着广泛的临床应用。

关键词: 定量CT, CT, 呼吸功能, 肺气肿, 临床应用

Abstract:

BACKGROUND: With the development of CT imaging technology, CT images can clearly display pulmonary structure and measure pulmonary function. It is a new method for evaluation and research of pulmonary function.
OBJECTIVE: To summarize the analysis index and clinical application of CT pulmonary function, so as to early discover and accurately monitor respiratory diseases in clinic.
METHODS: Articles about imaging indexes and clinical applications of CT pulmonary function were searched from CNKI and PubMed, published between January 1989 and May 2010 with key words “computed tomography, pulmonary function, quantitative CT” in both Chinese and English. We mainly selected these articles in the authoritative journals or recently published. A total of 26 Chinese articles and 287 English articles were collected, and 20 articles were included in the final analysis.
RESULTS AND CONCLUSION: CT pulmonary function could reflect the changes of pulmonary function by measurement of lung volume, density and pixel index, so as to reveal the pathological anatomy and pathophysiology of pulmonary tissues. It is a valuable method to early discover and monitor respiratory diseases. CT pulmonary function measurement can be used in quantitative analysis of chronic obstructive pulmonary diseases and emphysema, prediction of pulmonary functional reserve after lung cancer surgery.

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