中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (44): 8335-8338.doi: 10.3969/j.issn.1673-8225.2010.44.041

• 器官移植临床实践 clinical practice of organ transplantation • 上一篇    下一篇

微粒皮漂浮与皮浆移植修复特重度烧伤患者创面的疗效对比

张明珠1，周桂芬2，董运凤3，齐长春1，赵志伟4，郭振存5，董俐坤6，李兴华1，董来成1，裴银辉2   

  1. 1河北钢铁集团唐山钢铁有限责任公司医院烧伤科，河北省唐山市　063020，2华北煤炭医学院，河北省唐山市  063020；3唐山市工人医院烧伤科，河北省唐山市　063020；4山西省烧伤救治中心,山西省太原市030000；5二五五部队医院烧伤科，河北省唐山市　063020；6唐山市中心血站机采科，河北省唐山市　063020
  • 出版日期:2010-10-29 发布日期:2010-10-29
  • 通讯作者: 裴银辉，男，1970年生，河南省郑州市人，汉族，教授，硕士生导师，1993华北煤炭医学院毕业，主要从事免疫学方面的研究及教学工作。 Yinhuipei70@163.com
  • 作者简介:张明珠，男，1966年生，吉林省浑江市人，汉族，主任医师，1993年华北煤炭医学院毕业，主要从事烧伤整形方面临床及教学工作。 zmzhu1965@163.com

Curative effects of transplantation of micro-skin floating versus skin pulping for patients with extremely severe burn

Zhang Ming-zhu1, Zhou Gui-fen2, Dong Yun-feng3, Qi Chang-chun1, Zhao Zhi-wei 4, Guo Zhen-cun5, Dong Li-kun6, Li Xing-hua1, Dong Lai-cheng1, Pei Yin-hui2   

  1. 1 Department of Burns, Hospital of Tangshan Steel and Iron Co., Ltd, Tangshan  063020, Hebei Province, China; 2 North China Coal Medical College, Tangshan  063020, Hebei Province, China; 3 Department of Burns, Hospital of Workers, Tangshan  063020, Hebei Province, China; 4 Burns Treatment Center of Shanxi Province, Taiyuan  030000, Shanxi Province, China; 5 Department of Burns, the 255 Military Hospital, Tangshan  063020, Hebei Province, China; 6 Department of Blood Machine Division, Blood Center Bank of Tangshan, Tangshan  063020, Hebei Province, China
  • Online:2010-10-29 Published:2010-10-29
  • Contact: Pei Yin-hui, Professor, Master’s supervisor, North China Coal Medical College, Tangshan 063020, Hebei Province, China Yinhuipei70@163.com
  • About author:Zhang Ming-zhu, Chief physician, Department of Burns, Hospital of Tangshan Steel and Iron Co., Ltd, Tangshan 063020, Hebei Province, China zmzhu1965@163.com

PDF

459

被引次数

4

摘要：

背景：采用微粒皮漂浮的方法行微粒皮移植已成为近30年来修复特重度烧伤创面经典术式，并取得了良好的临床疗效。然而，采用皮浆涂抹的方法行微粒皮移植也能取得较好的治疗效果，但对此两种疗效方法的对比尚无报道。
目的：观察皮浆移植法行微粒皮移植的临床疗效，并与常规微粒皮漂浮移植法进行对比。
方法：选取特重烧伤患者72例，采用自身对照的方法，每例患者选取较为对称、创面性质相同的2处Ⅲ度烧伤切痂创面进行对照。皮浆移植组采用皮浆涂抹的方法行微粒皮移植，微粒皮漂浮组采用微粒皮漂浮的方法行微粒皮移植。应用网格计数法统计微粒皮移植后3，4和5周末2组创面愈合率。
结果与结论：移植后第3，4和5周末扩张比在12.5∶1以下的2段，两组创面愈合率基本相近(P > 0.05)，提示微粒皮漂浮与皮浆移植均为治疗大面积深度烧伤的良好方法。扩张比在12.6∶1以上的2段，微粒皮漂浮组明显优于皮浆移植组(P < 0.05或P < 0.01)，表明当扩张比超过12.5∶1的情况下，有必要选用微粒皮漂浮法行微粒皮移植。

关键词: 微粒皮, 皮浆, 漂浮, Ⅲ度烧伤, 创面愈合, 疗效, 组织移植

Abstract:

BACKGROUND: It has already become being close to the style restoring classical skill to adopt the method of floating to transplant tautologies micro-skin during the past 30 years, and has got the fine clinical curative effect. But by means of skin pulping auto-epithelium grafting has also got fairly good clinical effect. However, the effect of these two treatment methods of the comparative study has not been reported.
OBJECTIVE: To observe the clinical effects of the skin pulping auto-epithelium grafting and do a compare of clinical effects with the routine skill of antilogous micro-skin floating transplantation.
METHODS: A total of 72 severe burn patients were recruited. In each patient, 2 symmetrical spots of Ⅲ-degree burn post-escharectomy were selected and were divided equally into micro-skin floating group and skin pulping ones. The skin pulping group was transplanted by skin pulping, while the micro-skin floating group by floating. Wound healing rates of every section were analyzed at the end of 3, 4 and 5 weeks after micro-skin transplantation by grid counting. RESULTS AND CONCLUSION: The recovery rates of the first two sections with expansion ratio less than 12.5: 1 were similar at the end of 3, 4 and 5 weeks after transplantation (P > 0.05), but the ones of the later two sections (greater than 12.6: 1) were different, and the micro-skin floating group were obviously better then the skin pulping one at the same times (P < 0.05 or P < 0.01). Whether it was necessary to select the method of micro-skin floating depends on the condition that the expansion ratio was lager than 12.5: 1.

中图分类号: