中国组织工程研究 ›› 2016, Vol. 20 ›› Issue (46): 6937-6942.doi: 10.3969/j.issn.2095-4344.2016.46.013

• 组织构建基础实验 basic experiments in tissue construction • 上一篇    下一篇

人工耳蜗置入后患儿有意义听觉整合量表分数的变化

满国栋1,2,徐百成1,刘晓雯1,杨小龙3,蒲玉红1,陈兴建1,郭玉芬1   

  1. 1兰州大学第二医院耳鼻咽喉头颈外科,甘肃省兰州市  730000;2甘肃省肿瘤医院头颈肿瘤外科,甘肃省兰州市  730050;3甘肃省人民医院耳鼻咽喉头颈外科,甘肃省兰州市  730000
  • 收稿日期:2016-08-21 出版日期:2016-11-11 发布日期:2016-11-11
  • 通讯作者: 郭玉芬,主任医师,博士生导师,兰州大学第二医院耳鼻咽喉头颈外科,甘肃省兰州市730000
  • 作者简介:满国栋,男,1983年生,甘肃省兰州市人,满族,硕士,主要从事耳聋防治研究。
  • 基金资助:

    国家自然科学基金项目(81172765)

Effect of cochlear implantation in speech rehabilitation of children with severe sensorineural deafness: changes in the scores of Meaningful Auditory Integration Scale

Man Guo-dong1, 2, Xu Bai-cheng1, Liu Xiao-wen1, Yang Xiao-long3, Pu Yu-hong1, Chen Xing-jian1,
Guo Yu-fen1   

  1. 1Department of Otolaryngology, Head and Neck Surgery, Second Affiliated Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China; 2Department of Head and Neck Cancer Surgery, Gansu Provincial Cancer Hospital, Lanzhou 730050, Gansu Province, China; 3Department of Otolaryngology, Head and Neck Surgery, Gansu Provincial Hospital, Lanzhou 730000, Gansu Province, China
  • Received:2016-08-21 Online:2016-11-11 Published:2016-11-11
  • Contact: Guo Yu-fen, Chief physician, Doctoral supervisor, Department of Otolaryngology, Head and Neck Surgery, Second Affiliated Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China
  • About author:Man Guo-dong, Master, Department of Otolaryngology, Head and Neck Surgery, Second Affiliated Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China
  • Supported by:

    the National Natural Science Foundation of China, No. 81172765

摘要:

文章快速阅读:

文题释义:
人工耳蜗:是一种电子装置,由体外言语处理器将声音转换为一定编码形式的电信号,通过置入体内的电极系统直接兴奋听神经来恢复或重建聋人的听觉功能。近年来,随着电子技术、计算机技术、语音学、电生理学、材料学、耳显微外科学的发展,人工耳蜗已从实验研究进入临床应用,已被作为治疗重度聋至全聋的常规方法。
有意义听觉整合量表:是由美国印第安那医学院Pobbins在1991年设计完成的,主要用于评估儿童的听觉能力,包括患儿使用助听设备的情况、对声音的察觉能力和对声音的理解能力3方面的内容。其既可以用于儿童选配助听器前后或人工耳蜗置入前后的听觉能力评估,也可以用于指导听觉康复训练。
摘要
背景:
目前药物治疗或助听器均不能改善重度或极重度感音神经性耳聋患者的听力,多导人工耳蜗可恢复其听力,促进其言语发育。
目的:观察人工耳蜗置入后患儿言语康复的发展规律及影响因素,分析各影响因素与患儿言语康复效果的相关性。
方法:选择138例7岁以内重度以上感音神经性耳聋患儿,均接受人工耳蜗置入治疗,于置入前后进行听觉整合量表分数评估,同时分析年龄、性别、耳聋性质、置入前有无言语干预、人工耳蜗置入年龄、置入后时间、父母文化程度、家庭经济状况及置入后康复模式对听觉综合量级测试分数的影响。
结果与结论:性别、置入时间长短、耳蜗是否发育正常对患儿有意义听觉整合量表分数无影响(P > 0.05);患儿年龄越大有意义听觉整合量表分数越高(P=0),置入前进行单耳或双耳言语干预患儿的有意义听觉整合量表分数高于未进行言语干预的患儿(P=0.018,P=0),但单耳与双耳干预对有意义听觉整合量表分数无影响(P > 0.05);父母文化程度越高、家庭收入越高,患儿有意义听觉整合量表分数越高(P=0,P=0);接受专业学校教育康复培训患儿的有意义听觉整合量表分数高于家庭教育康复培训的患儿(P=0)。表明人工耳蜗置入可促进患儿听觉言语发育,置入年龄越大、置入前有言语干预、家庭经济收入较高、父母文化程度较高及置入后接受康复训练患儿的言语康复效果越好。

中国组织工程研究杂志出版内容重点:组织构建;骨细胞;软骨细胞;细胞培养;成纤维细胞;血管内皮细胞;骨质疏松组织工程
ORCID: 0000-0002-5130-6814(郭玉芬)

关键词: 组织构建, 组织工程, 人工耳蜗, 有意义听觉整合量表, 感音神经性耳聋, 言语康复效果, 国家自然科学基金

Abstract:

BACKGROUND: At present, neither medications nor hearing aids can improve auditory sense of patients with severe sensorineural deafness, and these patients are mostly treated by multi-channel cochlear implantation to restore their auditory sense and promote the development of language ability.  
OBJECTIVE: To identify the developmental law and influencing factors related to the rehabilitation of language ability in children with severe sensorineural deafness after cochlear implantation and to analyze the correlation of these influencing factors with speech rehabilitation in children.  
METHODS: Totally 138 children under 7 years old suffering from severe sensorineural deafness received cochlear implantation. Their auditory sense were accessed using the Meaningful Auditory Integration Scale (MAIS) before and after implantation, and their age, gender, nature of deafness, presence or absence of pre-operative language intervention, age of cochlear implantation, education level of their parents, family economic status, and post-operative rehabilitation approach were analyzed to find a correlation between these factors and their MAIS scores.  
RESULTS AND CONCLUSION: Gender, length of time after implantation, and development of cochlear showed no effect on MAIS scores of these children (P > 0.05); age of the patient was positively correlated with the MAIS score (P=0), and pre-operative single-ear or double-ear language intervention showed beneficial effect on the MAIS score (P=0.018, P=0), but no significant difference was detected between single-ear and double-ear interventions (P > 0.05); higher family income and higher education level of the parents were correlated with higher MAIS score (P=0, P=0); and those receiving professional in-school rehabilitation training got higher scores than those receiving only family rehabilitation training (P=0). These results suggest that the cochlear implantation significantly improves language development of children with severe sensorineural deafness, and better rehabilitation can be achieved if the child is treated at relatively older age, received pre-operative language intervention, and has a family with high income and parents with higher education level.

中国组织工程研究杂志出版内容重点:组织构建;骨细胞;软骨细胞;细胞培养;成纤维细胞;血管内皮细胞;骨质疏松组织工程

Key words: Cochlear Implants, Cochlear Implantation, Tissue Engineering

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