中国组织工程研究

中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (34): 6457-6460.doi: 10.3969/j.issn.2095-4344.2012.34.037

• 组织构建临床实践 clinical practice in tissue construction • 上一篇    

镍铬合金烤瓷修复体拆除前后患者血清镍铬含量的检测与评估

郭大伟1，滕敏华2，陈正岗1，翟浚江2，文 才2，田 艾2，孙宁远2，梁 星2   

  1. 1青岛市市立医院口腔科，山东省青岛市 266071；
    2四川大学华西口腔医院修复科，四川省成都市 610041
  • 收稿日期:2012-01-17 修回日期:2012-03-13 出版日期:2012-08-19 发布日期:2012-08-19
  • 通讯作者: 梁星，主任医师，教授，博士生导师，四川大学华西口腔医学院修复科，四川省成都市 610041 tengminhua@ 163.com
  • 作者简介:郭大伟☆，男，1974年生，山东省苍山县人，汉族，2010年四川大学毕业，博士，主治医师，主要从事口腔种植学及修复学的临床与基础研究。 gdavy@126.com

Detection and assessment of serum nickel and chromium levels in patients before and after the removal of the nickel-chromium alloy porcelain-fused-to-metal restoration

Guo Da-wei1, Teng Min-hua2, Chen Zheng-gang1, Zhai Jun-jiang2, Wen Cai2, Tian Ai2, Sun Ning-yuan2, Liang Xing2   

  1. 1Department of Stomatology, Qingdao Municipal Hospital, Qingdao 266071, Shandong Province, China;
    2Department of Prosthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, Sichuan Province, China
  • Received:2012-01-17 Revised:2012-03-13 Online:2012-08-19 Published:2012-08-19
  • Contact: Liang Xing, Doctoral supervisor, Professor, Chief physician, Department of Prosthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, Sichuan Province, China tengminhua@ 163.com
  • About author:Guo Da-wei☆, Doctor, Attending physician, Department of Stomatology, Qingdao Municipal Hospital, Qingdao 266071, Shandong Province, China gdavy@126.com

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被引次数

1

摘要：

背景：目前关于镍铬合金烤瓷修复体是否会对人体造成系统性影响的研究尚较少报道。
目的：通过对镍铬合金烤瓷修复体拆除前后患者血清中镍铬元素含量的测定，对其临床应用安全性进行科学评估。
方法：选取因怀疑镍铬烤瓷修复体的镍、铬元素对全身有影响，而要求拆除原修复体的患者69例，在修复体拆除前、拆后1个月，分别运用石墨炉原子吸收光谱法对患者血清中镍、铬含量进行检测，并按年龄、性别、修复体数目、修复体戴入时间以及修复体有无金属暴露等因素进行分组分析。
结果与结论：69例患者在镍铬烤瓷修复体拆除前后所测的血清镍、铬含量结果差异无显著性意义(P > 0.05)，而且患者的血清镍、铬含量与年龄、性别、修复体的数量、修复时间以及有无金属暴露等均无明显的相关性(P > 0.05)。提示镍铬合金烤瓷修复体所释放的镍、铬离子量微小，不足以对人体血清中的镍、铬含量造成影响。

关键词: 镍, 铬, 镍铬合金, 金属烤瓷, 血清镍, 血清铬

Abstract:

BACKGROUND: Currently, there are few reports on whether the nickel-chromium alloy porcelain-fused-to-metal (PFM) restoration has a systematic effect on the human body.
OBJECTIVE: To investigate the clinical security of the nickel-chromium alloy PFM, according to the assessment of the serum levels of nickel and chromium before and after the removal of the restoration.
METHODS: Sixty-nine patients were selected for the study, who suspected that nickel-chromium alloy PFM could affect their health and therefore came to hospital to ask for removal of the crown. The serum levels of nickel and chromium in these 69 patients were detected before and 1 month after the removal of the nickel-chromium alloy PFM restorations. In addition, the serum levels of nickel and chromium in these patients were analyzed according to their age, gender, the number and duration of PFM restorations, and whether the metal was exposed or not in restoration.
RESULTS AND CONCLUSION: There were no statistical differences between the serum levels of nickel and chromium in patients before and after the removal of the nickel-chromium alloy PFM restoration (P > 0.05). In addition, the serum levels of nickel and chromium in patients had nothing to do with gender, age, the number and duration of PFM restorations, and whether the metal was exposed or not in restoration (P > 0.05 ). The amount of nickel and chromium released from nickel-chromium alloy PFM is small, which cannot affect the serum levels of nickel and chromium in the human body.

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