中国组织工程研究

中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (13): 2336-2341.doi: 10.3969/j.issn.1673-8225.2012.13.013

• 数字化骨科 digital orthopedics • 上一篇    下一篇

植入式人工肛门括约肌系统的实现及动物实验***★

许茜茜，刘  华，颜国正   

  1. 上海交通大学电子信息与电气工程学院820研究所，上海市 200240
  • 收稿日期:2011-08-13 修回日期:2011-09-19 出版日期:2012-03-25 发布日期:2012-03-25
  • 通讯作者: 刘华，副教授，硕士生导师，上海交通大学电子信息与电气工程学院820研究所，上海市 200240 liuyuhua@sjtu.edu.cn
  • 作者简介:许茜茜★，女，1986年生，江苏省江阴市人，汉族，上海交通大学电子信息与电气工程学院在读硕士，主要从事精密仪器与机械研究。xxxshelley2011@gmail.com
  • 基金资助:

    国家自然科学基金项目(30800235)、教育部博士点基金新教师基金项目(20070248094)、上海交通大学“医工(理)交叉研究项目(YG2009ZD103)。

Implementation and animal experiment of an implantable artificial anal sphincter system

Xu Qian-qian, Liu Hua, Yan Guo-zheng   

  1. The 820 Research Institute, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai  200240, China
  • Received:2011-08-13 Revised:2011-09-19 Online:2012-03-25 Published:2012-03-25
  • Contact: author: Liu Hua, Master’s supervisor, Associate professor, the 820 Research Institute, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China liuyuhua@sjtu.edu.cn
  • About author:Xu Qian-qian★, Studying for master’s degree, the 820 Research Institute, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China xxxshelley2011@gmail.com
  • Supported by:

    the National Natural Science Foundation of China, No. 30800235*; Project of Doctoral Education Fund for New Teachers, Ministry of Education, No. 20070248094*; Cross Foundation Major Project of Engineering and Medicine of Shanghai Jiao Tong University, No. YG2009ZD103*

PDF

530

被引次数

16

摘要：

背景：研制新型的符合人体生理需求的人工肛门括约肌系统具有十分重要的意义。
目的：设计一种新型植入式人工肛门括约肌系统。
方法：利用无线通讯模块和压力传感器重建排便控制机制，并由经皮能量传输模块供电，采用机电系统模拟人体自然器官的功能，最终实现人体肛门括约肌的控制效果。
结果与结论：设计并实现了一种新型的植入式人工肛门括约肌系统，在重建排便机制和模型的基础上，一定程度上恢复肛门失禁患者的生物反馈控制能力，并带有经皮能量传输模块，为体内系统长期无缆式供电提供可能。该系统实现了植入式动物实验，完成了系统植入可行性和基本功能验证。
关键词：人工肛门括约肌；生物反馈控制；经皮能量传输；植入式动物实验；数字化医学 
doi:10.3969/j.issn.1673-8225.2012.13.013

关键词: 人工肛门括约肌, 生物反馈控制, 经皮能量传输, 植入式动物实验, 数字化医学

Abstract:

BACKGROUND: It is important to develop a new kind of implantable artificial anal sphincter system to meet the physiological needs of the human body.
OBJECTIVE: To design a new kind of implantable artificial anal sphincter system.
METHODS: Wireless communication model and pressure sensors were used to rebuild the mechanism of defection, and the power was supplied with transcutaneous energy transmission model. The electro-mechanical system was adopted to simulate the human natural organ to achieve the control efforts of human anal sphincter finally.
RESULTS AND CONCLUSION: A new kind of implantable artificial anal sphincter system was designed and accomplished. The bio-feedback control ability of anus incontinent patients could be recovered in some degree based on the reconstruction of defecation mechanism and model. The implantable artificial anal sphincter system had the module of transcutaneous energy transmission that could provide long-time wireless power for the internal system. The animal experiment was accomplished to verify the feasibility to implant the implantable artificial anal sphincter system and its basic function.

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