中国组织工程研究

中国组织工程研究 ›› 2026, Vol. 30 ›› Issue (10): 2608-2617.doi: 10.12307/2026.637

• 组织构建相关数据分析 Date analysis of organization construction • 上一篇    下一篇

电针促进周围神经再生实验研究的现状与热点：电针参数、针灸效应与分子机制

刘同岩1，李  元2，孙  玮1，姚  冰2，方姗姗2，周凌云2   

  1. 1黑龙江中医药大学，黑龙江省哈尔滨市  150006；2哈尔滨医科大学附属第一医院，黑龙江省哈尔滨市  150001


  • 收稿日期:2025-05-06 接受日期:2025-06-19 出版日期:2026-04-08 发布日期:2025-08-30
  • 通讯作者: 周凌云，博士，主任医师，哈尔滨医科大学附属第一医院，黑龙江省哈尔滨市 150001
  • 作者简介:刘同岩，男，1995年生，汉族，黑龙江中医药大学在读博士，医师，主要从事针灸治疗神经系统疾病研究。
  • 基金资助:
    国家自然科学基金项目(82074524)，项目负责人：周凌云；黑龙江中医药大学研究生创新科研项目(2024yjscx103)，项目负责人：刘同岩

Current status and hotspot analysis of experimental research on electroacupuncture intervention for peripheral nerve regeneration: electroacupuncture parameters, acupuncture effects and molecular mechanisms

Liu Tongyan1, Li Yuan2, Sun Wei1, Yao Bing2, Fang Shanshan2, Zhou Lingyun2   

  1. 1Heilongjiang University of Traditional Chinese Medicine, Harbin 150006, Heilongjiang Province, China; 2First Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China
  • Received:2025-05-06 Accepted:2025-06-19 Online:2026-04-08 Published:2025-08-30
  • Contact: Zhou Lingyun, MD, Chief physician, First Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China
  • About author:Liu Tongyan, MD candidate, Physician, Heilongjiang University of Traditional Chinese Medicine, Harbin 150006, Heilongjiang Province, China; First Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China
  • Supported by:
    the National Natural Science Foundation of China, No. 82074524 (to ZLY); Heilongjiang University of Traditional Chinese Medicine Graduate Student Innovative Scientific Research Project, No. 2024yjscx103 (to LTY)

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摘要：


文题释义：
文献计量学：是一门基于数学和统计方法实现对某领域文献定量化分析的学科，主要研究论文的产出、引用、合作网络、研究现状及发展趋势，以揭示科研规律。CiteSpace和VOSviewer是文献计量最常用的两种分析软件。
实验研究：广义的实验研究是一种通过人为控制和操纵变量来探究因果关系的研究方法。此文章特指医学研究中的动物实验研究，与临床研究相对，其以动物模型模拟人类疾病或生理过程，用于探索疾病机制、评估干预措施或药物安全性和有效性，是基础医学向临床转化的重要桥梁。

背景：当前，电针治疗周围神经损伤实验研究开展迅速，涉及不同的神经与疾病种类，针对这一领域的文献计量学梳理有重要的学术价值。
目的：总结电针干预周围神经损伤实验研究领域的发展历程、研究现状、热点和未来趋势。
方法：在中国知网(CNKI)、生物医学文献数据库(CBM)、Web of Science核心合集数据库中检索电针干预周围神经损伤的实验研究文献，检索时限为各数据库建库至2024年12月，经过筛选、去重及数据清洗后，利用CiteSpace与VOSviewer软件对数据进行总结并生成可视化图谱。
结果与结论：共纳入432篇文献(其中CNKI 181篇，CBM 186篇，Web of Science 65篇)，发文量呈现波动性上升趋势，有一定数量的核心作者，但作者、机构分布松散，尚未形成核心作者群，中文文献有599个关键词节点，英文文献有364个关键词节点，主要病种为单神经损伤、神经病理性疼痛、糖尿病性周围神经病，研究层次逐渐深入，目前研究围绕电针适宜参数、针灸效应与分子机制展开，星形胶质细胞与小胶质细胞分别处于中、英文突现时间段内。未来应继续加大电针干预周围神经损伤实验研究力度，通过加强作者、机构交流，与材料学、高通量测序等高新技术相结合，寻找新的突破点，共同促进高质量研究文章的产出，推动该领域发展。
https://orcid.org/0009-0009-4837-6107(刘同岩)

中国组织工程研究杂志出版内容重点：干细胞；骨髓干细胞；造血干细胞；脂肪干细胞；肿瘤干细胞；胚胎干细胞；脐带脐血干细胞；干细胞诱导；干细胞分化；组织工程

关键词: 电针, 周围神经损伤, 实验研究, 文献计量学, 现状, 热点分析

Abstract: BACKGROUND: Currently, experimental research on electroacupuncture intervention for peripheral nerve injury is rapidly developing, involving various nerves and disease types. A bibliometric analysis of this field holds significant value.
OBJECTIVE: To summarize the development history, current research status, hotspots and future trends in the field of experimental research on electroacupuncture intervention in peripheral nerve injury.
METHODS: Literature related to electroacupuncture intervention for peripheral nerve regeneration was retrieved from CNKI, CBM, and Web of Science Core Collection databases up to December 2024. After screening, deduplication, and data cleaning, CiteSpace and VOSviewer were used to analyze the data and generate visual knowledge maps.
RESULTS AND CONCLUSION: A total of 432 articles were included (181 from CNKI, 186 from CBM, and 65 from the Web of Science Core Collection). The annual publication count showed a fluctuating upward trend, with a number of core authors identified, but author and institutional distributions remained scattered without forming a cohesive core group. Chinese-language articles contained 599 keyword nodes, while English-language articles had 364. The main disease focuses were mononeuropathy, neuropathic pain, and diabetic peripheral neuropathy. Research depth has progressively increased, with current studies concentrating on optimal electroacupuncture parameters, acupuncture effects, and molecular mechanisms for these conditions. Astrocytes and microglia emerged as burst terms in Chinese and English literature, respectively. Future efforts should intensify experimental research on electroacupuncture intervention for peripheral nerve injury by enhancing collaboration among authors and institutions, integrating advanced technologies such as materials science and high-throughput sequencing, to identify new breakthroughs. These measures will collectively promote high-quality research output and advance the field.


Key words: electroacupuncture, peripheral nerve injury, experimental research, bibliometrics, current status, hotspots

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