Chinese Journal of Tissue Engineering Research ›› 2019, Vol. 23 ›› Issue (4): 551-555.doi: 10.3969/j.issn.2095-4344.0573

Previous Articles     Next Articles

Numerical simulation of bifurcating blood vessel flow under overload

Bao Mixia1, 2, Zhou Ping1, Guo Feng2, Wang Jia2   

  1. 1the Third Xiangya Hospital of Central South University, Changsha 410013, Hunan Province, China; 2Hunan Provincial People’s Hospital, Changsha 410016, Hunan Province, China
  • Online:2019-02-08 Published:2019-02-08
  • About author:Bao Mixia, Master candidate, the Third Xiangya Hospital of Central South University, Changsha 410013, Hunan Province, China; Hunan Provincial People’s Hospital, Changsha 410016, Hunan Province, China
  • Supported by:

    the Natural Science Foundation of Hunan Province, No. 2018JJ3295 (to WJ)

Abstract:

BACKGROUND: Human body has a certain tolerance limit to overload, so load beyond certain strength will cause damage to the human body. The effect of overload on the flow of blood vessels is an important medical topic in manned space.

OBJECTIVE: To study the flow patterns of pulsating blood vessels under unconventionally gravity load in a typical three-dimensional model of cervical artery.
METHODS: Based on normal pulse cycle, we considered 0.85 seconds as pulsating blood supply cycle. The blood flow ratio of main vessels and branch vessels was 7:3. Based on Fluent software, the effects of gravity overload on the flow characteristics of typical blood vessels were analyzed by adding gravity load (1 G of overload at direction of X+; 2 G of overload at direction of Y+) to the momentum source of the control equation.
RESULTS AND CONCLUSION: The changes of transient flow field structure and shear stress of wall under gravity overload were obtained. Because of the influence of Y+ direction of overload, the bifurcating vessels had obvious difference in velocity distribution, size of reflux region and shear stress distribution at different time. Under the effect of overweight load, the blood flow in the main blood vessel decreased and serious reflux occurred. The shear stress on the wall of the branching blood vessel was obviously higher than that on the main blood vessel.

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程

Key words: Stress, Mechanical, Hemodynamics, Computers, Analog, Tissue Engineering

CLC Number: