Chinese Journal of Tissue Engineering Research ›› 2021, Vol. 25 ›› Issue (5): 807-812.doi: 10.3969/j.issn.2095-4344.3019

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The global competitive situation of cardiac tissue engineering based on patent analysis

Xu Dongzi, Zhang Ting, Ouyang Zhaolian   

  1. Institute of Medical Information/Medical Library, CAMS & PUMC, Beijing 100020, China
  • Received:2020-01-16 Revised:2020-01-18 Accepted:2020-03-20 Online:2021-02-18 Published:2020-12-01
  • About author:Xu Dongzi, Master, Research assistant, Institute of Medical Information/Medical Library, CAMS & PUMC, Beijing 100020, China
  • Supported by:
    the National Key Research and Development Program of China, No. 2016YFC0104805

Abstract: BACKGROUND: Tissue engineering is the best way to repair or replace organ failure or tissue defects. From the theoretical point of view to the research in many fields, tissue engineering has developed very rapidly. As cardiovascular disease has become one of the most dangerous factors that endanger human health, research on cardiac tissue engineering has made tremendous progress.
OBJECTIVE: To provide advices and references for the development and innovation of cardiac tissue engineering based on patent analysis in the field of cardiac tissue engineering that reveals the global competitive situation of cardiac tissue engineering.
METHODS: We qualitatively and quantitatively analyze the number and development tendency, technology birthplaces, target markets, applicants, inventors and technical fields of patents in the field of liver tissue engineering in nearly 20 years. The data visualization method is used to present the current status and tendency of global cardiac tissue engineering technology development and China's development status.
RESULTS AND CONCLUSION: The technology for cardiac tissue engineering has been evolved rapidly and highly innovative, with invention patents accounting for 93.91%. The scale of technological development in the field of cardiac tissue engineering in China is not expanded as large as that in the United States, but the growth rate is far faster than that in the United States, and it has accumulated a certain number of high-quality technological achievements, becoming the second largest source of technology in the world. The United States is the most concerned target market in the field of cardiac tissue engineering, and the Chinese market currently ranks fourth. Chinese cardiac tissue engineering has developed rapidly in recent years, growing much faster than that in the United States. There are three institutions in China that has mounted to the front of the world in terms of technology development. Due to a lack of technological achievements with high potential market value, there is still a certain gap between China and the United States. Chinese inventors have achieved certain results in this field, mainly in enterprises. The main fields of technological innovation in this field are heart valve covering materials and cell scaffolds. Through an in-depth and comprehensive analysis of patents in the field of cardiac tissue engineering, it can be found that the global development of cardiac tissue engineering is active and innovative, but generally lacks high-quality results. The United States is the most concerned target market in this field and the most important technology birthplace, whereas China is at a stage of rapid development in this field. In order to improve technological competitiveness, enterprises and universities should strengthen cooperation and focus on research hot spots.

Key words: cardiac tissue engineering, competitive situation, patent analysis, patentometrics

CLC Number: