Absorbable material versus Kirschner wire fixation for fractures of the lateral humeral condyle in children: a Meta-analysis

doi:10.3969/j.issn.2095-4344.0741

Abstract

Abstract:

BACKGROUND: Currently, there is no explicit evidence-based medicine evidence to prove the merits or demerits of absorbable materials in the treatment of fractures of the lateral humeral condyle in children.

OBJECTIVE: To evaluate the clinical efficacies of open reduction with absorbable material versus open reduction with Kirschner wire fixation for lateral condylar fracture of the humerus in children.

METHODS: WanFang, VIP, CNKI, CBMdisc, EMbase, PubMed were retrieved for controlled trials concerning open reduction with absorbable material versus open reduction with Kirschner wire fixation for treating lateral condylar fracture of the humerus in children. After data extraction and quality evaluations, RevMan 5.3 software was used for systematic review. Postoperative functional recovery of the elbow joint, average hospitalization expenses, adverse events, delayed union, postoperative infection, nerve injury and deformity of the elbow were compared in patients undergoing different treatments.

RESULTS AND CONCLUSION: A total of seven articles, involving 449 children with lateral condylar fracture of the humerus, were included for this Meta-analysis. Children in test group received open reduction with absorbable material, while those in control group were subjected to open reduction with Kirschner wire fixation. For treating lateral condylar fracture of the humerus in children, no significant inter-group difference existed in the aspects of postoperative functional recovery of the elbow joint [odds ratio (OR)=0.72, 95% confidence interval (CI) (0.37, 1.41), P=0.34]; postoperative delayed union [OR=0.46, 95% CI (0.16, 1.30), P=0.14]; deformity of the elbow [OR=0.70, 95% CI (0.24, 2.10), P=0.53]. Less adverse events and postoperative infections were observed in the test group compared with the control group [OR=0.17, 95% CI (0.08, 0.38), P < 0.000 1; OR=0.09, 95% CI (0.02, 0.38), P=0.001]. However, up to now, we knew of no comparable data concerning average hospitalization expenses and indicators for nerve injury between the two groups. To conclude, compared with Kirschner wire fixation, open reduction with absorbable material can achieve similar effects on lateral condylar fractures of the humerus, but has better effects to prevent adverse events and postoperative infection. Further investigation on large-scale, double-blind, high-quality randomized controlled trials is warranted for confirming our results.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

Key words: Absorbable Implants, Humeral Fractures, Child, Meta-Analysis, Tissue Engineering

CLC Number:

R318

Chen Xing-guang, Lu Min-hua, Lu Lin, Wang Xiao-dong, Zou Cheng-da, Pu Chong. Absorbable material versus Kirschner wire fixation for fractures of the lateral humeral condyle in children: a Meta-analysis[J]. Chinese Journal of Tissue Engineering Research, 2018, 22(14): 2290-2296.

Figures/Tables 8

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