Chinese Journal of Tissue Engineering Research ›› 2016, Vol. 20 ›› Issue (21): 3156-3162.doi: 10.3969/j.issn.2095-4344.2016.21.017

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 Effect of lightweight polypropylene mesh versus standard polypropylene mesh on tension-free repair of inguinal hernia

Zhou Xian-feng1, Ma Cong1, Wang Qi1, Hu Hao2   

  1. 1Department of General Surgery, First People’s Hospital of Huainan, Huainan 232007, Anhui Province, China; 2Department of General Surgery, Second Affiliated Hospital of Anhui Medical University, Hefei 230601, Anhui Province, China
  • Received:2016-03-19 Online:2016-05-20 Published:2016-05-20
  • About author:Zhou Xian-feng, Master, Associate chief physician, Department of General Surgery, First People’s Hospital of Huainan, Huainan 232007, Anhui Province, China

Abstract:

BACKGROUND: Lightweight polypropylene mesh with lower content of polypropylene is added with some absorbable ingredients, and will these ingredients cause adverse reactions in vivo?

 

OBJECTIVE: To compare the effect of lightweight polypropylene mesh and standard polypropylene mesh on tension-free repair of inguinal hernia.

 

METHODS: Forty patients with inguinal hernia were randomly divided into two groups (n=20 per group): the patients were treated by lightweight polypropylene mesh as experimental group and those treated by standard polypropylene mesh as control group. At 2 days after surgery, white blood cell counts, neutrophils percentage and level of C-reactive protein were detected. Furthermore, pain scores as well as discomfort incidence and complications were assessed and recorded at 2 days, 1, 3 and 6 months after surgery, respectively.

 

RESULTS AND CONCLUSION: There were no significant differences in postoperative complications between two groups. White blood cell counts and neutrophils percentage in the experimental group were significantly lower than those in the control group (P < 0.05), but the level of C-reactive protein had no significant difference. Besides, pain scores had no significant difference between the two groups, but the postoperative discomfort incidence in the experimental group was significantly decreased compared with the control group(P < 0.05). In conclusion, lightweight polypropylene mesh can reduce postoperative inflammation and discomfort incidence.

 

 

 

Key words: Polyethylene, Hernia, Inguinal, Tissue Engineering

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