Chinese Journal of Tissue Engineering Research

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Prosthetic titanium mesh simultaneous implantation for the treatment of orbital facial defects after maxillectomy

Wen Li-ting, Qiao Li, Chen Fu-quan, Chen Xiao-dong, Shi Zhao-hui   

  1. Department of Otolaryngology and Head and Neck Surgery, Xijing Hospital, the Fourth Military Medical University of PLA, Xi’an  710032, Shaanxi Province, China
  • Received:2013-02-04 Revised:2013-03-20 Online:2013-05-21 Published:2013-05-21
  • Contact: Shi Zhao-hui, M.D., Attending physician, Department of Otolaryngology and Head and Neck Surgery, Xijing Hospital, the Fourth Military Medical University of PLA, Xi’an 710032, Shaanxi Province, China
  • About author:Wen Li-ting, Physician, Department of Otolaryngology and Head and Neck Surgery, Xijing Hospital, the Fourth Military Medical University of PLA, Xi’an 710032, Shaanxi Province, China zhadjun@fmmu.edu.cn

Abstract:

BACKGROUND: Facial bone defects may occur after maxillary trauma or tumor resection, which may influence the appearance and the life quality of the patients, so the early repairing has great significance to the patients.   
OBJECTIVE: To investigate the long-term effect of prosthetic titanium mesh simultaneous implantation for the treatment of orbital facial defect after maxillectomy.
METHODS: Twenty-one maxillary sinus malignancy patients received maxillectomy, and the maxillary sinus malignancy patients treated with titanium mesh simultaneous implantation to repair orbital floor and anterior maxillary sinus wall bone defects in the Department of Otolaryngology and Head and Neck Surgery, Xijing Hospital, the Fourth Military Medical University of PLA from June 2009 to January 2013 were selected. Among the 21 patients, four cases received partial resection of maxilla, 11 cases received maxillectomy, and six cases received maxillary extended resection. The effect of titanium mesh on the repair of midface and orbital defects after maxillectomy was observed during follow-up.
RESULTS AND CONCLUSION: All the patients obtained one stage healing after titanium mesh simultaneous implantation with symmetrical facial contour and normal eyeball function, and the patients were basically satisfied with the facial appearance. All the patients could eat soft diet and had clear language after treated with prosthetic titanium mesh implantation; two cases had partial titanium mesh implant exposure after adjuvant radiotherapy, and healed after nearby flap transplantation. The results show that titanium mesh can be used for facial repair and reconstruction in the maxillary defect patients, and has significant effect in restoring facial appearance, preventing diplopia occurrence, repairing late function and improving life quality.

Key words: biomaterials, biomaterial academic discussion, titanium mesh, titanium plate, mini-titanium plate, prosthesis, implants, maxillectomy, bone reconstruction, facial defects, repair and reconstruction, maxillary sinus, sinus tumor, fracture

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