Abstract:

BACKGROUND: Bone tissue defects due to bone tumor are a difficult problem in clinic, and how to repair bone defects is a hotspot in the orthopedics.
OBJECTIVE: To introduce the application of different bone filling materials in bone tumors, and to observe the clinical effects of calcium sulfate bone graft combined with autologous bone to repair bone defects induced by bone tumors.
METHODS: A computer-based search of PubMed and CNKI was performed to retrieve relavent articles published 2001-01/2011-01 using the keywords of “bone filled materials, bone tumor, bone defect” in English and Chinese, respectively. Totally 40 articles were retrieved, and finally 24 met the requirment.
RESULTS AND CONCLUSION: Bone filling materials for bone tumor-induced bone defects are mainly divided into autologous bone, allograft bone, artifical materials. Some scholars have achieved good results by using composite materials. Each kind of materials has its own advantages and disadvantages in the repair of bone defects. Up to now, there is not an ideal filling material for bone defects. The bone filling materials produced by using bone tissue engineering technology may be one of the future developmental direction.