Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (25): 4687-4690.doi: 10.3969/j.issn.1673-8225.2011.25.031

Previous Articles     Next Articles

Tissue-engineered bone materials for repair of long bone segmental defects

Li Chang-geng, Xu Jian-qiang   

  1. Department of Orthopedics, General Hospital of the Second Artillery Force of Chinese PLA, Beijing  100088, China
  • Received:2011-01-04 Revised:2011-03-10 Online:2011-06-18 Published:2014-01-10
  • Contact: Xu Jian-qiang, Associate professor, Associate chief physician, Department of Orthopedics, General Hospital of the Second Artillery Force of Chinese PLA, Beijing 100088, China xjjq@sina.com
  • About author:Li Chang-geng★, Studying for master’s degree, Attending physician, Department of Orthopedics, General Hospital of the Second Artillery Force of Chinese PLA, Beijing 100088, China lichanggeng1974@163.com
  • Supported by:

    Military Medical and Health Science Research Fund, No.06G018*

PDF

460

Abstract:

BACKGROUND: Bone graft, artificial substitute replacement, bone lengthening and other repair methods for long bone segmental defects have been used in clinic, but they have their own limitations.
OBJECTIVE: To review and summarize the current methods of bone defect treatment, and to analyze the developmental prospect of the treatment for the long bone defect.
METHODS: The first author searched PubMed Database and Chinese Medical Current Contents to retrieve articles about long bone defect repair published 2000-01 to 2010-12. The keywords were “bone defect, bone tissue engineering, artificial bone, bone transplantation, therapy” in English and Chinese. Older articles and repetitive studies were excluded.
RESULTS AND CONCLUSION: Thirty-three articles were included in final analysis. Repair methods for long bone segmental defects include autogenous bone graft, allograft, bone lengthening, bone substitute transplantation. Tissue engineered bone to repair bone defects has become the hot topic nowadays, but there are many urgent questions to be solved. The tissue engineered bone is a promising means of treating bone defects.

CLC Number: