Abstract:

BACKGROUND: To evaluate the effect of cartilage repair materials on the repair of knee cartilage injuries so as to support a certain experience for medical and scientific research workers.
METHODS: An electronic search of Wanfang database was performed using the keywords of “biomaterials; articular cartilage; injuries; repair” to retrieve articles about repair materials for knee cartilage injuries published between 2000-01 and 2011-03. Repetitive articles, review and Meta analysis were excluded, and finally 26 articles were eligible.
RESULTS: Knee cartilage injuries are commonly seen in sports-induced injuries. The main treatment is to repair cartilage defects in the knee with autogenous bone graft. The new cartilage substitute material is still in the phase of animal tests. The long-term efficacy and biomechanical changes in model animals need further studies, and then the related clinical trials can be done.
CONCLUSION: There are many important and difficult problems to be explored in the basic and clinical research concerning the repair of knee cartilage injuries. However, a new progress from biomaterial grafts to reconstructed active bone is realized in the repair of knee cartilage injuries. With the development and research of various new-type materials, the repair of knee cartilage injuries can be increasingly perfect.