Abstract:

BACKGROUND: It is urgent in clinic to design a kind of medical equipment that is microinvasive, safe and effective for treatment of colorectal perforation and anastomotic leakage.
OBJECTIVE: To design a kind of medical equipment that can be put into the colon through the anus to aid the treatment of colorectal perforation and anastomotic leakage, and then to test the performance so as to verify its safety and reliability for clinical application.
METHODS: The colon sac duct was made of medical silicon rubber and medical polyurethane. Then, the outer capsule flexibility, deformation pressure of inner ducts and outer capsule, colon sac duct leak pressure were tested so as to assess the feasibility and safety of the duct in clinical application.
RESULTS AND CONCLUSION: The outer capsule deformation pressure of the colon sac duct was (30.42±0.46) kPa for medical silicon rubber and (30.73±0.29) kPa for medical polyurethane. The inner duct deformation pressure values were (5.96±0.22) kPa and > 100 kPa, respectively. The colon sac duct leakage gas pressure was (59.23±1.25) kPa and (60.01±1.45) kPa, respectively. The rigidity of the colon sac duct was not better enough, thus easily leading to the stricture and closure of inner tube cavity. The deformation pressure of the outer capsule was somewhat lower, but there was no significant difference (P=0.088), leakage gas pressure of sac duct was no significant difference (P=0.213). The colon sac duct made of polyurethane possessed simple structure and excellent performance: easy to operation, safety and reliability.