Platelet-rich fibrin versus collagen membrane in the repair of gingival defects

doi:10.3969/j.issn.2095-4344.2016.16.008

Abstract

Abstract:

BACKGROUND: Previous studies have found that platelet-rich fibrin has a good ability to induce gingival soft tissue repair and regeneration.
OBJECTIVE: To observe the effects of platelet-rich fibrin versus collagen membrane on gingival soft tissue healing, and to evaluate the ability of platelet-rich fibrin to repair gingival defects.
METHODS: Twenty-two patients (2 premolar teeth and 20 molars) scheduled for premolar or molar removal or ridge preservation due to various reasons were selected and randomized into two groups. Bio-Oss was implanted into the extraction socket followed by covering with platelet-rich fibrin or collagen membrane. Healing time and healing rate of gingival defects were detected to evaluate the ability of platelet-rich fibrin to promote gingival tissue healing at 1-2 weeks after Bio-Oss implantation.
RESULTS AND CONCLUSION: The healing time was (12.17±2.25) days in the platelet-rich fibrin group and (17.30±2.58) days in the collagen group. The healing rate of the platelet-rich fibrin group was notably higher than that in the collagen membrane group at 1 and 2 weeks after Bio-Oss implantation. These findings indicate that platelet-rich fibrin is better than collagen membrane to improve the healing of gingival soft tissues with a shorter healing time.
中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

Key words: Gingiva, oft Tissue Injuries, Wound Healing, Tissue Engineering

Dong Lu, Xiao Qiong, Yang Qin-qiu, Sun Yong, Chen Hong-liang. Platelet-rich fibrin versus collagen membrane in the repair of gingival defects[J]. Chinese Journal of Tissue Engineering Research, 2016, 20(16): 2340-2346.

Figures/Tables 3

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