Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (47): 7545-7549.doi: 10.3969/j.issn.2095-4344.2015.47.001

    Next Articles

Vertebroplasty with polymethylmethacrylate bone cement treats elderly osteoporotic thoracolumbar vertebral compression fractures

Tang Xiao-ming, Dai Jian, Zhu Guo-tai, Sun Hai-lang, Fei Hao-dong   

  1. Huai’an First People’s Hospital, Nanjing Medical University, Huaian 223300, Jiangsu Province, China
  • Received:2015-11-05 Online:2015-11-19 Published:2015-11-19
  • Contact: Fei Hao-dong, Master, Attending physician, Huai’an First People’s Hospital, Nanjing Medical University, Huaian 223300, Jiangsu Province, China
  • About author:Tang Xiao-ming, Master, Attending physician, Huai’an First People’s Hospital, Nanjing Medical University, Huaian 223300, Jiangsu Province, China

Abstract:

BACKGROUND: At present, percutaneous vertebroplasty has been widely used in clinical treatment of osteoporotic vertebral fractures. Considering the limitations of the underlying disease in elderly patients (> 65 years of age) at surgery, the relevant detailed studies have gradually attracted the attention of clinicians.
OBJECTIVE: To compare and analyze the clinical effects of vertebroplasty with bone cement and conventional fracture reduction for elderly osteoporotic thoracolumbar fractures.
METHODS: Totally 24 elderly patients with osteoporotic thoracolumbar fractures were voluntarily divided into bone cement treatment and conservative treatment groups (n=12 per group) and subjected to vertebroplasty with polymethylmethacrylate bone cement and conventional reduction therapy, respectively.
RESULTS AND CONCLUSION: Compared with the conservative treatment group, the visual analog scale scores, Oswesty dysfunction index and Cobb angle were significantly reduced in the bone cement treatment group, while the degree of anterior vertebral compression was increased. These results suggest that minimally invasive spine treatment is conducive to improve the fracture healing and enhance the quality of life in elderly patients with osteoporotic vertebral compression fractures in stable conditions. 
中国组织工程研究杂志出版内容重点:生物材料;骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性;组织工程

Key words: Vertebroplasty, Osteoporosis, Tissue Engineering