Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (22): 3604-3608.doi: 10.3969/j.issn.2095-4344.2015.22.029

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Injured vertebra pedicle screw fixation and cross-segment pedicle screw fixation for thoracolumbar fracture: a meta-analysis  

Wu Yi, He He-bei, Sun Yong-jian, Li Wei-cheng, Ding Chao   

  1. the Fifth Affiliated Hospital of Southern Medical University, Guangzhou 510900, Guangdong Province, China
  • Received:2015-04-12 Online:2015-05-28 Published:2015-05-28
  • Contact: He He-bei, Master, the Fifth Affiliated Hospital of Southern Medical University, Guangzhou 510900, Guangdong Province, China
  • About author:Wu Yi, Associate chief physician, the Fifth Affiliated Hospital of Southern Medical University, Guangzhou 510900, Guangdong Province, China

Abstract:

BACKGROUND: Thoracolumbar fracture becomes more in the clinic. The fixation manner of thoracolumbar fracture is controversial. Injured vertebra pedicle screw fixation or traditional cross-segment pedicle screw fixation are controversial and lack the support of evidence-based medicine.
OBJECTIVE: To evaluate the outcomes of injured vertebra pedicle screw and cross-segment pedicle screw fixation for thoracolumbar fractures.
METHODS: According to Cochrane system evaluation, the following databases were retrieved: National Library of Medicine database, China National Knowledge Infrastructure, Wanfang database and VIP database. Conference proceedings were searched by hand. The retrieval time ranged from 2005 to March 2015. Randomized controlled trials were collected. Meta-analysis was performed by using Cochrane Collaboration Revman 4.2.
RESULTS AND CONCLUSION: By screening, a total of 14 clinical controlled trials were selected, including 956 patients. Meta-analysis results showed that postoperative Cobb angle was improved significantly in the vertebral pedicle screw group than in the cross-segment pedicle screw fixation group (OR=-2.72, 95%CI: -3.08--2.35, P < 0.01). Correction rate of the vertebral height was higher in the vertebral pedicle screw group than in the cross-segment pedicle screw fixation group (OR=7.45, 95%CI:6.94-7.97, P < 0.01). The failure rate was lower in the vertebral pedicle screw group than in the cross-segment pedicle screw fixation group (OR=0.12, 95%CI: 0.05- 0.27, P < 0.01). Results verify that postoperative Cobb angle improved significantly after the injured vertebrae pedicle screw and cross-segment pedicle screw fixation for thoracolumbar fractures. The height was obviously corrected and fewer complications were caused such as implant failure. The fixation effect was good. 

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程

 

Key words: Tissue Engineering, Fractures, Bone, Thoracic Vertebrae, Lumbar Vertebrae

CLC Number: