Semi-fascial semi-flap transplantation for repairing skin and soft tissue defects of the hand and foot: univariate and multivariate logistic regression analysis

doi:10.3969/j.issn.2095-4344.2014.51.021

Abstract

Abstract:

BACKGROUND: Transplantation of free anterolateral semi-fascial semi-flap is used clinically to repair soft tissue defects of the hand and foot, but the transplantation fails in some patients under the same conditions.
OBJECTIVE: To observe a new method for repairing soft tissue defects of the hand and foot and to study the clinical effects.
METHODS: Totally 150 cases were subjected to transplantation of free semi-fascial semi-flap of the anterolateral thigh. The semi-flap was placed on the functional area of the hand or foot, and the semi-fascia was placed on the non-functional area. At 7-10 days after flap survival, semi-fascial granulation remodeling was carried out, and skin graft was used to cover the wound. Then, the factors influencing the success of flap transplantation were subjected to univariate and multivariate logistic regression analysis.
RESULTS AND CONCLUSION: Free semi-fascial semi-flap transplantation had obvious therapeutic effects, and only one case appeared to have complete necrosis. Age and smoking history were found to be factors influencing the success of free semi-fascial semi-flap transplantation. In the successful transplantation group, the number of cases younger than 60 years old and without a history of smoking was significantly higher than that in the transplantation failure group. After 5 years of follow-up, only one patient was not satisfied with the therapeutic effects, and two cases had no fully recovery in the functional areas. The results confirm that free semi-fascial semi-flap repair of hand-foot soft tissue defects can achieve good postoperative results, and the main factors that influence the success of the surgery are age and smoking history.

中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

全文链接：

Key words: tissue engineering, tendinopathy, soft tissue injuries, transplantation

CLC Number:

R318

Li Zi-hua, Huang Ruo-qiang, Lv Tu. Semi-fascial semi-flap transplantation for repairing skin and soft tissue defects of the hand and foot: univariate and multivariate logistic regression analysis[J]. Chinese Journal of Tissue Engineering Research, 2014, 18(51): 8310-8314.

Figures/Tables 3

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