Abstract:

BACKGROUND: The use of bio-membrane guided bone regeneration in maxillary sinus augmentation is a research hotspot in implantology at present.
OBJECTIVE: To investigate the osteogenic effect of guided bone regeneration in maxillary sinus augmentation using collagen membranes.
METHODS: The first maxillary molars of nine adult female beagle dogs were extracted and full-thickness flap was reflected bilaterally, then the sinus floors were lifted with simultaneous implantation. Bio-Oss was placed into the new space under the sinus membrane. On the experimental side in each dog, the bio-membrane covered the osteotomy window. On the control side, the flap was sutured directly, and was not covered by bio-membrane. Two animals were sacrificed at 4, 12, and 24 weeks after surgery, respectively. Gross observation, biomechanical testing and histological examinations were performed.
RESULTS AND CONCLUSION: In gross view, new bone formation was observed in all maxillary sinuses. The pull-out force increased with time. At week 24, a significant difference in the pull-out force was noted between the two groups (P < 0.05). Histomorphbomatrical analysis showed much more new calluses at the experimental group than the control group at weeks 12 and 24 after surgery (P < 0.05). The bio-membrane guided bone regeneration has a better effect on new bone formation in the sinus augmentation.

Key words: maxillary sinus, bone regeneration, dental implantation, biofilms