Dispersion degree of a small-dose bone cement

doi:10.3969/j.issn.2095-4344.0186

Abstract

Abstract:

BACKGROUND: During the percutaneous vertebroplasty, the optimal dose of bone cement that can bring favorable cement dispersion and remodel the biomechanical balance of the fractured vertebrae remains controversial.

OBJECTIVE: To investigate the dispersion degree of small dose of bone cement in vertebroplasty.

METHODS: In this experiment, 18 sheep selected with the same condition were randomly divided into three groups (group A, group B, group C), 6 in each group. A model of thoracolumbar vertebral compression fracture (T₁₂, L₁, L₂) was made in each sheep. The injected volume of bone cement in groups A, B, C was 15%, 20%, 25% of the average volume of adjacent vertebral bodies, respectively. Postoperative CT images were used to evaluate the bone cement dispersion. Dispersion degree of bone cement among the three groups was compared by the Kruskal-Wallis test.

RESULTS AND CONCLUSION: There was no statistical difference in the dispersion degree of bone cement among the three groups, and the excellent and good rate of dispersion was over 80%. To conclude, the optimal dose of bone cement injected into the fractured vertebra is 15% of the average volume of adjacent vertebral bodies, which can achieve good dispersion degree and restore the biomechanical stability of the vertebral body.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

Key words: Vertebroplasty, Diffusion Magnetic Resonance Imaging, Animal Experimentation, Tissue Engineering

CLC Number:

R318

Sun Hai-bo, Qi Ming, Hai Yong, Wang Xin-kuan, Zhang Wu-jun, He Ying-hua, Li Hua, Zhang Guo-fu, Zhao Ji-yang, Cao Lian-xu. Dispersion degree of a small-dose bone cement[J]. Chinese Journal of Tissue Engineering Research, 2018, 22(14): 2140-2145.

Figures/Tables 5

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