Clinical application of three-dimensional printing implant template in the restoration of free-end missing teeth

doi:10.3969/j.issn.2095-4344.0185

Abstract

Abstract:

BACKGROUND: Three-dimensional (3D) printing technology is currently one of the most advanced industrial manufacturing technologies. The surgical template prepared based on the 3D printing technology is mainly made of resin, and a great improvement in its accuracy is required. However, the clinical application of the surgical template made of metal is rarely reported.

OBJECTIVE: To evaluate the clinical value of 3D-printing implant template in the restoration of free-end missing teeth.

METHODS: A prospective study was conducted in 64 enrolled patients with free end-tooth defects. All the patients were randomly assigned to receive traditional implant template (control group, n=32) or 3D-printing implant template (study group, n=32), and 3-6 months later, the patients were subjected to crown restoration. At 6 months after crown restoration, cone beam computed tomography was performed to compare the deviation of the implant tip and neck (including vertical, buccolingual, mesial-distal). Success rate and chewing rate were compared between the two groups at 6 months after crown restoration; patient satisfaction assessment was done and compared between the two groups at 1 year after crown restoration.

RESULTS AND CONCLUSION: There were no significant differences between the two groups in the success rate and chewing rate (98.7% vs. 95.6%; 97.4% vs. 97.1%, P > 0.05). The vertical, buccolingual, mesial-distal deviations of the implant tip were significantly lower in the study group than the control group (P < 0.05), while there was no difference in the vertical and buccolingual deviations of the implant neck between the two groups (P > 0.05), and the mesial-distal deviation of the implant neck was significantly lower in the study group than the control group (P < 0.05). In addition, there was no difference in the patient satisfaction between the study and control groups (94% vs. 91%, P > 0.05). To conclude, the 3D printing implant template can effectively reduce implant excursion based on the assurance of therapeutic efficacy and patient satisfaction, which is of great significance in the restoration of free-end tooth loss.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

Key words: Dental Implantation, Dental Implants, Mastication, Tissue Engineering

CLC Number:

R318

Zhao Dian-cai, Nie Yu-jie, Ouyang Shan, Lin Xiao-hui, Hu Xi-juan. Clinical application of three-dimensional printing implant template in the restoration of free-end missing teeth[J]. Chinese Journal of Tissue Engineering Research, 2018, 22(14): 2179-2184.

Figures/Tables 5

References

[1] Yoshino K,Nishibori M,Fujiseki M,et al.Loss of teeth in positions mesially adjacent to implant-supported fixed dentures: a retrospective clinical survey.Int J Prosthodont. 2015;28(2):158-160.

[2] Campos CH,Gonçalves TM,Garcia RC.Implant-Supported Removable Partial Denture Improves the Quality of Life of Patients with Extreme Tooth Loss.Braz Dent J. 2015;26(5): 463-467.

[3] 何女,钱江,赵佳佳,等.数字化导板用于牙种植的三维精度分析[J].口腔颌面外科杂志,2015,25(2):117-120.

[4] Schepers RH,Raghoebar GM,Vissink A,et al.Accuracy of fibula reconstruction using patient-specific CAD/CAM reconstruction plates and dental implants: A new modality for functional reconstruction of mandibular defects.J Craniomaxillofac Surg.2015;43(5):649-657.

[5] 蔡洁明,褚烛天,舒传继,等.种植牙技术对老年牙列游离端缺失修复的疗效分析[J].现代生物医学进展,2015,15(13):2509-2511.

[6] 汤雨龙,惠瑞宗,曹志强,等.3D打印技术在口腔种植导板制作中的应用[J].解放军医药杂志,2015,27(11):32-35.

[7] 何女,钱江,赵佳佳,等.数字化导板用于牙种植的三维精度分析[J].口腔颌面外科杂志,2015,25(2):117-120.

[8] Jin T,Hou X,Li P,et al.A Novel Method of Automatic Plant Species Identification Using Sparse Representation of Leaf Tooth Features.PloS One.2015;10(10):139482.

[9] 向梅,张宇.种植导板的设计制作及临床应用前景[J].中国组织工程研究,2015,19(3):488-492.

[10] Schneider D,Schober F,Grohmann P,et al.In-vitro evaluation of the tolerance of surgical instruments in templates for computer-assisted guided implantology produced by 3-D printing.Clin Oral Implants Res.2015;26(3):320-325.

[11] 范园园,宋岩,高宇飞,等.前牙美学区牙槽骨宽度不足牙种植的临床观察[J].临床口腔医学杂志,2017,33(2):101-104.

[12] 宫苹.牙种植修复中的咬合重建[J].口腔颌面外科杂志, 2016, 26(6):381-384.

[13] 何女,钱江,赵佳佳,等.数字化导板用于牙种植的三维精度分析[J].口腔颌面外科杂志,2015,2(1):117-120.

[14] 马竞.上颌后牙区口腔3D导板种植精确性研究[J].中国医学工程, 2015,23(5):88,90.

[15] Wilde F,Hanken H,Probst F,et al.Multicenter study on the use of patient-specific CAD/CAM reconstruction plates for mandibular reconstruction.Int J Comput Assist Radiol Surg, 2015,10(12):2035-2051

[16] 周小义,刘尧,叶斌,等.3D打印导板辅助髁突骨软骨瘤及继发复杂牙颌面畸形的手术治疗[J].口腔医学研究, 2017,33(2): 166-169.

[17] Anssari Moin D,Derksen W,Verweij JP,et al.A Novel Approach for Computer-Assisted Template-Guided Autotransplantation of Teeth With Custom 3D Designed/Printed Surgical Tooling.An Ex Vivo Proof of Concept.J Oral Maxillofac Surg. 2016;74(5):895-902.

[18] 张悦,徐连来.计算机导航在口腔种植牙领域的应用[J].临床口腔医学杂志,2015,31(10):603-606.

[19] 李志刚,刘宁,郝智莉,等.牙种植全程导航技术的临床应用[J].中华口腔医学杂志,2015,50(1):47-49.

[20] 王佐林,王方.牙种植修复中的咬合重建、数字化技术、无牙颌种植修复方法--“争鸣与共识”种植论坛(第二季)学术共识[J].口腔颌面外科杂志,2016,26(3):153-155.

[21] 徐普,李晓妮,徐邢环宇,等.牙槽骨黏骨膜骨瓣新技术在牙种植手术中的应用[J].中华口腔医学杂志,2016,51(11):688-690.

[22] Khalil W,EzEldeen M,Van De Casteele E,et al.Validation of cone beam computed tomography-based tooth printing using different three-dimensional printing technologies.Oral Surg Oral Med Oral Pathol Oral Radiol.2016;121(3):307-315.

[23] 汤雨龙,惠瑞宗,曹志强,等.3D打印技术在口腔种植导板制作中的应用[J].解放军医药杂志,2015,27(11):32-35.

[24] Nickenig HJ,Wichmann M,Terheyden H,et al.Oral health-related quality of life and implant therapy: A prospective multicenter study of preoperative, intermediate, and posttreatment assessment.J Craniomaxillofac Surg. 2016;44(6):753-757.

[25] Bilhan H,Bilmenoglu C,Urgun AC,et al.Comparison of the Primary Stability of Two Implant Designs in Two Different Bone Types: An In Vitro Study.Int J Oral Maxillofac Implants. 2015;30(5):1036-1040.

[26] Mo H,Mo T,Zhuang X,et al.Clinical application of the new type Metal Pierced Surgical Template based on 3D printing technology: a 1-year prospective study.Clin Oral Impl Res. 2014;4(8):128-133.

[27] Cornelius CP,Smolka W,Giessler GA,et al.Patient-specific reconstruction plates are the missing link in computer-assisted mandibular reconstruction: A showcase for technical description.J Craniomaxillofac Surg. 2015;43(5): 624-649.

[28] 魏宁.不同种植系统口腔种植临床病例的临床疗效分析[J].中外医疗,2017,36(1):61-62,68.

[29] 张宏伟,李春茹.即刻种植和常规种植在牙齿缺失修复中的临床价值对比[J].黑龙江医药科学,2017,40(1):115-116.

[30] 石磊,黄盛兴,刘慧凤,等.前牙区数字化即刻种植即刻修复病例报道及文献回顾[J].口腔疾病防治,2017,25(2):119-122.

[31] Zheng P, Yao Q, Xu P,et al.Application of computer-aided design and 3D-printed navigation template in Locking Compression Pediatric Hip Plate[Formula: see text] placement for pediatric hip disease.Int J Comput Assist Radiol Surg. 2017;12(5):865-871.