Cut-off point of visceral fat area: predicting low bone mass in women

doi:10.12307/2021.283

Abstract

Abstract: BACKGROUND: In recent years, concerns have been paid to the relationship between obesity, especially abdominal obesity, and bone mineral density. Studies have concluded that visceral fat area is a risk factor for reducing bone mineral density. There are also some studies suggesting an interaction between age, visceral fat area and bone mineral density.
OBJECTIVE: To explore the correlation between body composition and bone mineral density, and to predict the risk cut-off point of visceral fat area for low bone mass.
METHODS: We retrospectively analyzed visceral fat area and bone mineral density measured by quantitative CT and bioelectrical impedance analysis in the Health Management Center, the First Affiliated Hospital of Zhengzhou University. Pearson correlation and multivariate linear regression analyses were used to analyze the correlation between body composition and bone mineral density, and multivariate Logistic regression analysis was used to analyze the correlation between body composition and low bone mass. Receiver characteristic operator curve was plotted to determine the cut-off point value of visceral fat area that predicts low bone mass.
RESULTS AND CONCLUSION: With the increase of age, bone mineral density gradually decreased, visceral fat area gradually increased, and basal metabolic rate gradually decreased. Multivariate linear regression analysis showed that age and visceral fat area were negatively correlated with bone mineral density. Multivariate Logistic regression analysis indicated that the visceral fat area of postmenopausal women was related to low bone mass. The cut-off point value of visceral fat area under receiver characteristic operator curve predicting low bone mass and osteoporosis in postmenopausal women was 117.85 cm2. In addition to age, visceral fat area is a risk factor for predicting osteoporosis. In order to reduce the incidence of osteoporosis and the medical and economic burden, we should strengthen the management of fat reduction in early-stage postmenopausal women.

Key words: low bone mass, female, bone mineral density, visceral fat area, quantitative CT, bioelectrical impedance analysis

CLC Number:

Qin Qian, Yang Yang, Chen Jingfeng, Wang Shoujun, Ding Suying. Cut-off point of visceral fat area: predicting low bone mass in women[J]. Chinese Journal of Tissue Engineering Research, 2021, 25(35): 5577-5581.

Figures/Tables 7

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