Chinese Journal of Tissue Engineering Research ›› 2020, Vol. 24 ›› Issue (24): 3911-3917.doi: 10.3969/j.issn.2095-4344.2721
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Li Kaiming1, Zhu Liguo1, Zhang Qing1, Li Linghui2, Xie Rui1, Chen Ming2, Liang Long1, Lin Chengyu1, Hou Xiaozhou1
Received:
2019-12-10
Revised:
2019-12-14
Accepted:
2020-01-16
Online:
2020-08-28
Published:
2020-08-17
Contact:
Zhang Qing, MD, Chief physician, Doctoral supervisor, Second Department of Spine, Wangjing Hospital of China Academy of Chinese Medical Sciences, Beijing 100102, China
Li Linghui, MD, Attending physician, Comprehensive Department of Orthopedics, Wangjing Hospital of China Academy of Chinese Medical Sciences, Beijing 100102, China
About author:
Li Kaiming, Doctoral candidate, Second Department of Spine, Wangjing Hospital of China Academy of Chinese Medical Sciences, Beijing 100102, China
Supported by:
the Special Project of Capital Health Research and Development, No. 2018-2-4162; the National Natural Science Foundation of China, No. 81674005; the Fundamental Research Funds for the Central Public Welfare Research Institutes, No. ZZ10-015
CLC Number:
Li Kaiming, Zhu Liguo, Zhang Qing, Li Linghui, Xie Rui, Chen Ming, Liang Long, Lin Chengyu, Hou Xiaozhou. Zolidronic acid combined with percutaneous kyphoplasty in the treatment of osteoporotic compression fractures: a meta-analysis of bone density improvement, recurrent vertebral fractures prevention, and long-term efficacy evaluation[J]. Chinese Journal of Tissue Engineering Research, 2020, 24(24): 3911-3917.
2.3.2 目测类比评分 5篇文献比较了治疗后1周、6个月、12个月的目测类比评分[7-11]。亚组分析结果显示研究间存在显著异质性(I2=88%),选用随机效应模型分析。4篇文献比较了治疗后1周的目测类比评分,结果显示两组间比较差异无显著性意义[MD=0.14,95%CI(-0.30,0.57),P=0.54];2篇文献比较了治疗后6个月的目测类比评分,试验组低于对照组[MD=0.46,95%CI(0.18,0.75),P=0.002];5篇文献报道了治疗后12个月的目测类比评分,试验组低于对照组[MD=0.85,95%CI(0.20,1.50),P=0.01],见图4。总体结果表明在改善疼痛评分方面,远期内相比唑来膦酸组效果更佳显著。 "
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