中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (48): 9011-9014.doi: 10.3969/j.issn.1673-8225.2011.48.020

• 数字化骨科 digital orthopedics • 上一篇    下一篇

智能人工肠内容物感知神经的初步研究

李建国1，史福军1，徐  帅1，陈  飞1，黄宗海1，郑锡俊2   

  1. 1南方医科大学附属珠江医院普通外科，广东省广州市  510282
    2华南理工大学国家大学科技园，广东省广州市510640
  • 收稿日期:2011-08-04 修回日期:2011-09-09 出版日期:2011-11-26 发布日期:2011-11-26
  • 通讯作者: 黄宗海，博士，主任医师、教授，博士生导师，南方医科大学附属珠江医院普通外科，广东省广州市 510282 drhuangzh@yahoo.com.cn
  • 作者简介:李建国☆，男，1973年生，河南省开封市人，汉族，南方医科大学在读博士，主治医师，主要从事胃肠道肿瘤的微创治疗及基因治疗的研究。 lijianguo0420@163.com
  • 基金资助:

    广东省科技计划基金资助项目(2009A030200014)。

Preliminary study of intelligent artificial intestinal content sensory nerve

Li Jian-guo1, Shi Fu-jun1, Xu Shuai1, Chen Fei1, Huang Zong-hai1, Zheng Xi-jun2   

  1. 1Department of General Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou  510282, Guangdong Province, China
    2National Science Park of South China University of Technology, Guangzhou  510640, Guangdong Province, China
  • Received:2011-08-04 Revised:2011-09-09 Online:2011-11-26 Published:2011-11-26
  • Contact: Huang Zong-hai, Doctor, Chief physician, Professor, Doctoral supervisor, Department of General Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China drhuangzh@yahoo.com.cn
  • About author:Li Jian-guo☆, Studying for doctorate, Attending physician, Department of General Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China lijianguo0420@163.com
  • Supported by:

    the Science and Technology Plan Foundation of Guangdong Province, No. 2009A030200014*

PDF

383

被引次数

4

摘要：

背景：现有的人工肛门括约肌都缺乏感知大便的功能，患者控制排便主要是通过自己的习惯而不是根据肠道内是否存在大便的实际情况来决定排便。
目的：研究能够感知不同肠内容物状态的人工感知神经。
方法：选用20只健康新西兰兔，于近结肠远端约10 cm肠管制作肠管内容物固体、流体、气体、空虚状态4种模型。各个状态的每段肠管随意选取5个测量点，利用超声波“智能人工肠内容物感知神经”系统对新西兰兔近结肠内4种状态肠内容物进行判断。
结果与结论：固体、流体、气体、空虚状态的正确判断率分别为96%，99%，100%，100%。提示该超声波探测系统可有效感知肠道内是否具有内容物和分辨肠管内容物的不同状态。

关键词: 智能, 感觉神经, 肠内容物, 状态, 超声波系统

Abstract:

BACKGROUND: Present artificial anal sphincter lacks awareness of the stool, and patients control their defecation mainly through their habits rather than the existence of the stool in the gut.
OBJECTIVE: To research whether artificial intestinal content sensory nerve could distinguish different status of intestinal contents, so as to lay the basis for the research and development of intelligent artificial anal sphincter (IAAS).
METHODS: Twenty healthy New Zealand rabbits were used, and the experiments were performed on the distal part of proximal colon of the rabbits. Five positions were randomly chosen on each proximal colon as the measuring points, and an intelligent artificial intestinal content sensory nerve was used to judge the solid, liquid, gaseous, and vacant status of the contents inside the colon lumen.
RESULTS AND CONCLUSION: The rate of the right judgment about the solid, liquid, gaseous, and vacant status of the contents were 96%, 99%, 100%, 100% respectively. This “intelligent artificial intestinal content sensory nerve” could be used to judge whether or not the feces exists and to distinguish various status of contents inside the intestinal lumen. Using ultrasound to detect the information of different status of intestinal lumen may be an effective method.

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