中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (39): 7384-7387.doi: 10.3969/j.issn.1673-8225.2011.39.041

• 骨与关节综述 bone and joint review • 上一篇    下一篇

计算机模拟建模及应用：微波消融治疗心房颤动的温度场

张会娟，丁金立，南  群，刘有军   

  1. 北京工业大学生命科学与生物工程学院，北京市  100124
  • 收稿日期:2011-04-21 修回日期:2011-06-14 出版日期:2011-09-24 发布日期:2011-09-24
  • 通讯作者: 南群，博士，副教授，北京工业大学生命科学与生物工程学院，北京市 100124
  • 作者简介:张会娟★，女，1986年生，河北省保定市人，硕士研究生。 zhj_youxiang@163.com
  • 基金资助:

    国家自然科学基金资助项目(31070754、11072012、10872013)及北京市优秀人才资助项目(2010D005015000006)。

Thermal field of microwave ablation therapy for atrial fibrillation: Application of computer simulation

Zhang Hui-juan, Ding Jin-li, Nan Qun, Liu You-jun   

  1. College of Life Science and Bioengineering, Beijing University of Technology, Beijing  100124, China
  • Received:2011-04-21 Revised:2011-06-14 Online:2011-09-24 Published:2011-09-24
  • Contact: Nan Qun, Doctor, Associate professor, College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, China
  • About author:Zhang Hui-juan★, Studying for master’s degree, College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, China zhj_youxiang@163.com
  • Supported by:

    the National Natural Science Foundation of China, No. 31070754*, 11072012*,. 10872013*; Beijing Excellent Talents Fund, No. 2010D00 5015000006*

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摘要：

背景：心房颤动是临床上最为常见的持续性心律失常，微波消融是治疗房颤的一种新技术，在国内外临床应用时间短，经验不足。
目的：对国内外微波消融治疗心房颤动温度场的研究现状及新进展作一综述。
方法：应用计算机检索CNKI、EI、SCI数据库中关于微波消融温度场的文章，在标题和摘要中以“消融，心房颤动，微波，温度场”或“ablation，atrial fibrillation，microwave, thermal field”为检索词进行检索。
结果与结论：微波导管消融术对引起心律失常的关键部位(即靶点)进行精细标测，使靶点及邻近的心肌组织发生凝固性坏死，以破坏心动过速的病灶及折返途径，从而消除心律失常。在尽量减少对正常组织伤害的同时，保证消融切割线的连续性，对于房颤消融至关重要。实现温度场的计算机模拟能够全面反映温度场的分布规律，医护人员可以在热疗手术进行之前对治疗过程有比较直观的认识，提出比较详细的手术规划，并且可以在术中根据部分参数修正模拟结果和加热的时间与强度，达到理想的治疗效果。

关键词: 消融, 心房颤动, 微波, 温度场, 综述文献

Abstract:

BACKGROUND: Microwave ablation is a new technology for the surgical treatment of atrial fibrillation.
And we lack experience in the clinical application of microwave ablation both at home and abroad.
OBJECTIVE: To summarize the situation and progression about the study on thermal field of microwave ablation therapy for atrial fibrillation at home and abroad.
METHODS: The databases of CNKI, EI and SCI were selected to search the related articles about the thermal field of microwave ablation. The keywords were “ablation, atrial fibrillation, microwave, thermal field” in Chinese and English.
RESULTS AND CONCLUSION: Microwave catheter ablations make refined mapping of targeted spots which induce arrhythmia, cause coagulative necrosis to targeted spots and the adjacent cardiac tissue, and make damage to tachycardia lesions and pathway to eliminate arrhythmia. Computer simulation of thermal field can comprehensively reflect the thermal distribution and help medical workers to get an intuitive understanding of the therapeutic process before ablation surgery and put forward a detailed surgical plan. Simulation results, heating time and intensity can be modified during surgical operation according to certain parameters to achieve desired treatment results.

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