中国组织工程研究 ›› 2026, Vol. 30 ›› Issue (27): 7088-7094.doi: 10.12307/2026.863

• 人工假体Artificial prosthesis • 上一篇    下一篇

解剖仿生重建外旋肌群联合轮匝带修复在单侧人工股骨头置换中的应用

马在超1,2,麦麦提依不巴吉·阿不都卡迪尔2,3,吕  青2,杨增强1,2,李  标1,2,崔  泳2   

  1. 1新疆医科大学,新疆维吾尔自治区乌鲁木齐市  830054;2新疆医科大学第五附属医院,新疆维吾尔自治区乌鲁木齐市  830011;3中国医学科学院北京协和医院骨科,北京市  100730
  • 收稿日期:2025-11-11 接受日期:2026-01-24 出版日期:2026-09-28 发布日期:2026-05-14
  • 通讯作者: 崔泳,硕士,硕士生导师,主任医师,新疆医科大学第五附属医院,新疆维吾尔自治区乌鲁木齐市 830011
  • 作者简介:马在超,男,1999年生,山东省青岛市人,汉族,新疆医科大学在读硕士,医师,主要从事生物骨组织工程等相关研究。
  • 基金资助:
    国家自然科学基金项目(81960396),项目负责人:崔泳

Application of anatomical biomimetic reconstruction of the external rotators combined with repair of the zona orbicularis in unilateral artificial femoral head replacement

Ma Zaichao1, 2, Maimaitiyibubaji·Abudukadier2, 3, Lyu Qing2, Yang Zengqiang1, 2, Li Biao1, 2, Cui Yong2   

  1. 1Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China; 2Fifth Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, Xinjiang Uygur Autonomous Region, China; 3Department of Orthopedics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China
  • Received:2025-11-11 Accepted:2026-01-24 Online:2026-09-28 Published:2026-05-14
  • Contact: Cui Yong, MS, Master’s supervisor, Chief physician, Fifth Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, Xinjiang Uygur Autonomous Region, China
  • About author:Ma Zaichao, MS candidate, Physician, Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China; Fifth Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, Xinjiang Uygur Autonomous Region, China
  • Supported by:
    National Natural Science Foundation of China, No. 81960396 (to CY)

摘要:

文题释义:

解剖仿生重建:基于人体解剖学结构,通过仿生学理念与技术对组织或结构进行重建,以恢复其生理功能与生物力学特性的手术方法。
外旋肌群:髋关节周围负责使大腿向外旋转的肌群,主要包括梨状肌、闭孔内、外肌、上、下孖肌及股方肌,对维持髋关节稳定性与运动功能至关重要。
轮匝带:髋关节囊内的环形纤维韧带结构,环绕股骨颈基部,通过约束关节囊和增强关节密封性,参与维持髋关节的稳定性。

摘要
背景:老年髋部骨折术式选择相关研究的重点已从机械性结构修复,转向基于仿生医学原理的生物力学精准重建。尽管解剖复位修复理论得到广泛认同,但如何借助个性化诊疗方案,实现修复稳固性与关节活动范围的优化协调,依然有待进一步研究。 
目的:探讨解剖仿生重建外旋肌群联合轮匝带修复在单侧人工股骨头置换中的应用效果。
方法:采用回顾性队列研究,纳入2021年6月至2023年3月新疆医科大学第五附属医院收治的单侧老年股骨颈骨折患者124例,均采用后外侧入路人工股骨头置换术。综合分析患者临床资料以及结合术前医患沟通结果分为2组,试验组65例采用解剖仿生重建外旋肌群联合轮匝带修复,对照组59例采用常规缝合方法(将关节囊联合外旋肌群肌腱固定于大转子处)。分别记录两组患者手术时间、术中出血量、切口长度、切口愈合情况、住院时间、并发症发生率以及再入院率;比较两组患者术后目测类比评分、Harris评分、髋伸-屈活动度、内旋-外旋活动度,评估解剖仿生重建外旋肌群联合轮匝带修复技术在单侧人工股骨头置换中的临床应用价值。
结果与结论:①两组患者一般资料对比差异均无显著性意义(P > 0.05);②围术期相关指标:试验组和对照组分别出现1例、2例乙级愈合伤口,经积极抗感染、定期换药密切观察后切口愈合良好;试验组术中出血量、切口长度等方面均优于对照组,差异有显著性意义(P < 0.05);试验组手术时间长于对照组,但差异无显著性意义(P > 0.05);两组患者切口愈合情况以及住院时间相比差异无显著性意义(P > 0.05);③两组患者在完全负重活动时间方面差异无显著性意义(P > 0.05);与对照组相比,试验组患者术后目测类比评分(术后1个月除外)、Harris评分、髋伸-屈活动度、内旋-外旋活动度明显更优,表明试验组远期预后明显优于对照组;④两组术后髋关节髋臼外展角相比差异无显著性意义(P > 0.05);但与对照组相比,试验组术后前倾角明显更大(P < 0.05);⑤通过定期随访,无论是试验组还是对照组均未发现假体松动、假体周围感染、骨折;住院期间两组均未出现脱位,但出院后试验组和对照组各发生1例、3例脱位,经麻醉下手法复位,脱位情况均得到纠正,差异无显著性意义;⑥结果表明解剖仿生重建不仅能保障关节稳定性,还能实现更佳的功能预后,为临床术式选择提供了新的参考维度。

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱;骨折;内固定;数字化骨科;组织工程

关键词: ">解剖仿生重建, 外旋肌群, 关节置换, 骨折, 梨状肌, 关节囊, 韧带修复, 生物力学

Abstract: BACKGROUND: The current focus of related research on surgical techniques for elderly hip fractures has shifted from mechanical structural repair to biomechanically precise reconstruction based on the principles of bionic medicine. Although the theory of anatomical reduction and repair is widely accepted, how to achieve an optimal balance between repair stability and joint range of motion through personalized treatment plans still requires further investigation.
OBJECTIVE: To investigate the application effect of anatomical bionic reconstruction of the external rotator muscles combined with repair of the zona orbicularis in unilateral artificial femoral head replacement.
METHODS: A retrospective cohort study was conducted, including 124 elderly patients with unilateral femoral neck fractures admitted to the Fifth Affiliated Hospital of Xinjiang Medical University from June 2021 to March 2023. All patients underwent  artificial femoral head replacement via a posterolateral approach. Based on comprehensive analysis of clinical data and preoperative doctor-patient communication, the patients were divided into two group: 65 patients underwent anatomical bionic reconstruction of the external rotator muscles combined with repair of the zona orbicularis (trial group), while 59 patients received conventional suture (fixing the joint capsule combined with the external rotator tendon to the greater trochanter, control group). Operative time, intraoperative blood loss, incision length, wound healing, hospital stay, complication rates, and readmission rates were recorded in the two groups. Postoperative visual analog scale scores, Harris scores, hip flexion-extension range of motion, and internal-external rotation range of motion were compared between the two groups to evaluate the clinical application value of the anatomical bionic reconstruction technique in unilateral artificial femoral head replacement.
RESULTS AND CONCLUSION: (1) No significant differences were found in the general data between the two groups (P > 0.05). (2) Perioperative indicators: one case in the trial group and two cases in the control group had grade B healing wounds, which healed well after active anti-infection treatment and regular dressing changes. The trial group showed significantly better intraoperative blood loss and incision length than the control group (P < 0.05). Operative time was longer in the trial group compared with the control group, but the difference was not statistically significant (P > 0.05). No significant differences were observed in wound healing or hospital stay between the two groups (P > 0.05). (3) There was no significant difference in the time to full weight-bearing activity between the two groups (P > 0.05). Compared with the control group, the trial group showed significantly better postoperative visual analog scale scores (except at 1 month postoperatively), Harris scores, hip flexion-extension range of motion, and internal-external rotation range of motion, indicating that superior long-term prognosis in the trial group was significantly better than that of the control group. (4) No significant difference was found in postoperative acetabular abduction angle between the two groups (P > 0.05). However, the trial group had a significantly higher postoperative anteversion angle than the control group (P < 0.05). (5) During regular follow-up, no prosthetic loosening, periprosthetic infection, or fractures were observed in either group. No dislocations occurred during hospitalization in either group. After discharge, one case in the trial group and three cases in the control group experienced dislocation, all of which were successfully reduced by manipulation under anesthesia. The difference was not statistically significant. (6) The results indicate that anatomical bionic reconstruction not only ensures joint stability but also achieves better functional outcomes, providing a new reference dimension for clinical surgical selection.

Key words: ">anatomical bionic reconstruction, external rotator muscles, joint replacement, fracture, piriformis muscle, joint capsule, ligament repair, biomechanics

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