中国组织工程研究

中国组织工程研究 ›› 2022, Vol. 26 ›› Issue (9): 1318-1322.doi: 10.12307/2022.421

• 骨与关节生物力学Bone and joint biomechanics • 上一篇    下一篇

非均匀材料股骨在不同负荷情况下的生物力学分析

魏国强1，李云峰1，王  一1，牛晓芬1，车丽芳1，王海燕2，李志军2，史国鹏1，白  灵1，莫  凯1，张晨晨1，许阳阳1，李筱贺2，3   

  1. 1长治市人民医院康复医学科，山西省长治市   046000；内蒙古医科大学，2基础医学院解剖教研室， 3数字医学中心，内蒙古自治区呼和浩特市   010110
  • 收稿日期:2021-05-12 修回日期:2021-05-14 接受日期:2021-06-24 出版日期:2022-03-28 发布日期:2021-12-09
  • 通讯作者: 许阳阳，初级治疗师，长治市人民医院康复医学科，山西省长治市 046000 李筱贺，教授，内蒙古医科大学基础医学院解剖教研室，数字医学中心，内蒙古自治区呼和浩特市 010110
  • 作者简介:魏国强，男，1971年生，山西省长治市人，汉族，1995年长治医学院毕业，硕士，副主任医师，主要从事康复研究。 李云峰，女，1981年生，山西省长治市人，汉族，2007年长治医学院毕业，主管护师，主要从事康复研究。
  • 基金资助:
    国家自然科学基金(81460330)，项目负责人：李筱贺；国家自然科学基金(81560348，81860383，81260269)，项目负责人：李志军；内蒙古自治区科技计划项目(2019)，项目负责人：李筱贺；内蒙古教育厅青年科技英才项目(njyt-15-b05)，项目负责人：李筱贺；内蒙自治区科技计划项目(2016)，项目负责人：李筱贺；内蒙自治区科技计划项目(2019GG115)，项目负责人：李志军；内蒙古自治区科技创新引导项目(2017)，项目负责人：李筱贺；内蒙古自治区自然科学基金(2016MS08131，2020MS08124，2020LH08021)，项目负责人：李筱贺；内蒙古人社厅归国留学人员基金，项目负责人：李筱贺；内蒙古医科大学科技百万计划基金项目(YKD2017KJBW012)，项目负责人：王海燕；内蒙古医科大学后续科研项目(2020)，项目负责人：李筱贺；内蒙古医科大学科技转化项目(YKD2020CGZH009)，项目负责人：李筱贺；内蒙古自治区“草原英才”工程青年创新人才，项目负责人：李筱贺；内蒙古医科大学“治学”人才二类(2021)，项目负责人：李筱贺

Biomechanical analysis of non-uniform material femur under different loads

Wei Guoqiang1, Li Yunfeng1, Wang Yi1, Niu Xiaofen1, Che Lifang1, Wang Haiyan2, Li Zhijun2, Shi Guopeng1, Bai Ling1, Mo Kai1, Zhang Chenchen1, Xu Yangyang1, Li Xiaohe2, 3    

  1. 1Department of Rehabilitation Medicine, Changzhi City People’s Hospital, Changzhi 046000, Shanxi Province, China; 2Department of Anatomy, School of Basic Medicine, 3Center for Digital Medicine, Inner Mongolia Medical University, Hohhot 010110, Inner Mongolia Autonomous Region, China
  • Received:2021-05-12 Revised:2021-05-14 Accepted:2021-06-24 Online:2022-03-28 Published:2021-12-09
  • Contact: Xu Yangyang, Rehabilitation therapist, Department of Rehabilitation Medicine, Changzhi City People’s Hospital, Changzhi 046000, Shanxi Province, China Li Xiaohe, Professor, Department of Anatomy, School of Basic Medicine, and Center for Digital Medicine, Inner Mongolia Medical University, Hohhot 010110, Inner Mongolia Autonomous Region, China
  • About author:Wei Guoqiang, Master, Associate chief physician, Department of Rehabilitation Medicine, Changzhi City People’s Hospital, Changzhi 046000, Shanxi Province, China Li Yunfeng, Nurse-in-charge, Department of Rehabilitation Medicine, Changzhi City People’s Hospital, Changzhi 046000, Shanxi Province, China Wei Guoqiang and Li Yunfeng contributed equally to this article.
  • Supported by:
    National Natural Science Foundation of China, No. 81460330 (to LXH); National Natural Science Foundation of China, No. 81560348, 81860383, 81260269 (to LZJ); Science and Technology Planning Project of Inner Mongolia Autonomous Region, No. 2019 (to LXH); Young Talents in Science and Technology Project of Inner Mongolia Education Department, No. njyt-15-b05 (to LXH); Science and Technology Planning Project of Inner Mongolia Autonomous Region, No. 2016 (to LXH); Science and Technology Planning Project of Inner Mongolia Autonomous Region, No. 2019GG115 (to LZJ); Science and Technology Innovation Guidance Project of Inner Mongolia Autonomous Region, No. 2017 (to LXH); Natural Science Foundation of Inner Mongolia Autonomous Region, No. 2016MS08131, 2020MS08124, 2020LH08021 (to LXH); Returned Overseas Scholars Fund of Inner Mongolia Human Resources and Social Security Department (to LXH); Science and Technology Millions Fund Project of Inner Mongolia Medical University, No. YKD2017KJBW012 (to WHY); Follow-Up Research Project of Inner Mongolia Medical University, No. 2020 (to LXH); Science and Technology Transformation Project of Inner Mongolia Medical University, No. YKD2020CGZH009 (to LXH); Young Innovative Talents of the “Prairie Talents” Project in Inner Mongolia Autonomous Region (to LXH); “Study” Talent Category II of Inner Mongolia Medical University, No. 2021 (to LXH) 

PDF

81

摘要：

文题释义：
CT灰度值赋值：利用CT灰度的不同，将组织划分为不同的等级材料，利用数学公式将CT灰度值与弹性模量进行转换运算，将不同骨组织材料进行相应赋值，能够较真实地体现骨组织内部的复杂情况，使模型更加准确。
髋部骨折：可分为囊内骨折和囊外骨折，囊内骨折包括股骨颈头下骨折和经颈型骨折，囊外骨折包括股骨颈基底骨折、转子间骨折和转子下骨折。

背景：目前股骨有限元模型仅分析单一负荷下的生物力学特性，不同负荷条件下的骨应力应变分布有助于评估和预测疾病恢复情况并改善手术效果。
目的：通过建立股骨三维模型，探索人体在不同姿势下股骨近端力学分布特点，明确股骨易骨折危险区域。
方法：基于人体股骨CT影像资料，利用Mimics，Geomagic Studio，Hypermesh以及Abaqus等三维重建软件建立股骨有限元模型，沿重力方向，在股骨冠状面与矢状面，分别成角-20°，-10°，0°，+10°，+20°，共5组工况，股骨头施加力300 N，股骨下段添加固定约束，观察股骨不同位置在不同角度生理负荷作用下的应力与应变的分布特征。
结果与结论：在冠状面+10°与矢状面-20°股骨的应力值与应变值出现峰值，股骨应力值整体分布：股骨干>股骨转子下>股骨颈，股骨应变值整体分布：股骨干>股骨颈>股骨转子下。患者髋内收10°站立位下与髋外展20°站立位下会使得股骨应力值与应变值增大，股骨整体力学所受负荷会增大。

https://orcid.org/0000-0002-5139-1924 (魏国强) ；https://orcid.org/0000-0003-1730-9082 (李云峰)

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

关键词: 股骨, 三维重建, 有限元分析, 应力, 应变

Abstract: BACKGROUND: The current femoral finite element model analyzes only the biomechanical studies at a single load, and the stress strain distribution of the bones under different load conditions helps to evaluate and predict the disease recovery and improve the surgical results.  
OBJECTIVE: Through the establishment of a three-dimensional model of the femur, to explore the mechanical behavior of the proximal femur in different postures of the human body, and clarify the risk area of femur fracture.
METHODS:  Based on the CT image data of the human femur, Mimics, Geomagic Studio, Hypermesh and Abaqus and other three-dimensional reconstruction softwares were used to establish a finite element model of the femur. Along the direction of gravity, on the coronal and sagittal planes of the femur, the shape surfaces were angled at -20°, -10°, 0°, +10°, +20°, a total of five groups of working conditions, and the femoral head exerted a force of 300 N. The lower part of the femur added a fixed constraint. At different positions of the femur, the distribution characteristics of stress and strain were observed under angular physiological load.  
RESULTS AND CONCLUSION: The stress and strain of the femur peaked at +10° in the coronal plane and -20° in the sagittal plane. The overall distribution of femoral stress values was femoral shaft > subtrochanteric > femoral neck; the overall distribution of femoral strain values was femoral shaft > femoral neck > subtrochanteric. The stress value and strain value of the femur could increase under the standing position of 10° hip adduction and 20° of hip abduction, and the load on the overall mechanics of the femur could increase.

Key words: femur, three-dimensional reconstruction, finite element analysis, stress, strain

中图分类号: