中国组织工程研究

中国组织工程研究 ›› 2019, Vol. 23 ›› Issue (14): 2208-2214.doi: 10.3969/j.issn.2095-4344.1668

• 组织工程口腔材料 tissue-engineered oral materials • 上一篇    下一篇

Mis Seven种植体固定修复牙列缺失的短期效果评价

王丽萍1，陈伟鸿1，查 骏1，陈希立1，宿玉成2，方 颖1，董 豫1，郭雪琪1，葛林虎1   

  1. 1广州医科大学附属口腔医院，广州口腔疾病研究所，口腔医学重点实验室，广东省广州市 510140；2中国医学科学院，北京协和医院口腔种植中心，北京市 100032
  • 收稿日期:2018-12-26
  • 通讯作者: 葛林虎，教授，博士，院长，广州医科大学附属口腔医院，广州口腔疾病研究所，口腔医学重点实验室，广东省广州市 510140
  • 作者简介:王丽萍，女，1969年生，浙江省东阳市人，硕士，主任医师，主要从事口腔种植研究工作。
  • 基金资助:

    广东省科学技术厅项目(2013B021800186)，项目负责人：王丽萍；广东省中医药局项目(20162098)，项目负责人：王丽萍；荔湾区科技计划项目(2016080065)，项目负责人：王丽萍

Short-term efficacy evaluation of Mis Seven implant system repairing dentition loss

Wang Liping1, Chen Weihong1, Zha Jun1, Chen Xili1, Su Yucheng2, Fang Ying1, Dong Yu1, Guo Xueqi1, Ge Linhu1   

  1. 1Stomatology Hospital of Guangzhou Medical University, Key Laboratory of Oral Medicine, Guangzhou Institute of Oral Disease, Guangzhou 510140, Guangdong Province, China; 2Chinese Academy of Medical Sciences, Department of Dental Implantology of Peking Union Medical College Hospital, Beijing 100032, China
  • Received:2018-12-26
  • Contact: Ge Linhu, Professor, MD, Stomatology Hospital of Guangzhou Medical University, Key Laboratory of Oral Medicine, Guangzhou Institute of Oral Disease, Guangzhou 510140, Guangdong Province, China
  • About author:Wang Liping, Master, Chief physician, Stomatology Hospital of Guangzhou Medical University, Key Laboratory of Oral Medicine, Guangzhou Institute of Oral Disease, Guangzhou 510140, Guangdong Province, China
  • Supported by:

    the Project of Department of Science and Technology of Guangdong Province, No. 2013B021800186 (to WLP); the Project of Traditional Chinese Medicine Bureau of Guangdong Province, No. 20162098 (to WLP); the Science and Technology Program of Liwan District, No. 2016080065 (to WLP)

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摘要：

文章快速阅读：

 

文题释义：
种植义齿：是将替代天然牙根的种植体植入颌骨，获取类似于牙固位支持的修复体，其结构主要分3部分：种植体、基台、上部结构，种植体、基台及修复体共同承担固位、支持、力传导和恢复咀嚼功能。种植义齿修复基本解决了传统义齿修复游离端牙缺失或全口牙缺失的固位问题，较好地恢复了咀嚼、美观及发音功能。
牙列缺失：是指各种原因导致的整个牙弓上不存留任何天然牙或牙根，又称无牙颌。牙列缺失为一种常见病、多发病，多见于老年人，常见病因为龋病和牙周炎，牙列缺失严重影响牙齿原有的咀嚼、美观、辅助发音、生理功能等，会对患者身心带来很大影响，应尽早修复。
 
 
背景：Mis Seven种植体在口腔种植修复临床应用已越来越普及，而在牙列缺失患者中的临床应用尚有待研究。
目的：探讨Mis Seven种植系统在牙列缺失中固定修复临床应用的短期效果。
方法：纳入2015年4月至2017年12月因牙列缺失在广州医科大学附属口腔医院种植科行Mis Seven系统种植固定修复的患者19例，其中全口牙列缺失3例，单颌上颌牙列缺失6例，单颌下颌牙列缺失10例，种植牙颗数共134颗，所有病例均行种植固定一段式修复。修复后6，12，24个月随访，将临床检查、牙槽骨与种植体间影像表现及负载后修复效果作为评价指标。

结果与结论：①134颗种植体中因周围组织感染失败2颗，种植体修复前成功率为98.51%，修复后成功率为100%；②19例牙列缺失患者修复后义齿稳定性良好、咬合关系良好，无机械性并发症与生物并发症发生，修复体稳定率为100%；③修复后6，12，24个月，所有种植体周围骨组织垂直吸收小于0.2 mm，提示种植体无明显边缘骨吸收，所有种植体周围牙龈组织健康，未见不可愈合的炎症及过度角化现象；④结果表明，应用Mis seven种植系统在牙列缺失中固定修复短期疗效观察中能获得良好的临床效果。

ORCID: 0000-0002-3750-8946(王丽萍)

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

关键词: Mis seven种植系统, 牙列缺失, 种植固定修复, 存留率, 成功率, 边缘骨吸收, 临床效果, 义齿稳定性, 咬合关系

Abstract:

BACKGROUND: Mis Seven implant has become more and more popular in oral implant restoration, and the clinical application in dentate-deficient patients remains to be studied.

OBJECTIVE: To explore the short-term effects of the Mis Seven implant system on fixed restorations in dentition loss.
METHODS: Nineteen patients undergoing fixed dental prostheses with the Mis Seven system due to dentition loss at the Department of Implants of the Stomatological Hospital of Guangzhou Medical University between April 2015 and December 2017 were included. Three patients had missing maxillary and maxillary dentition and unilateral maxillary teeth. Six patients were loss of maxillary dentition, and there were 10 cases of unilateral mandibular dentition missing. The total dental implants were 134. All cases were implanted and fixed for one stage. Clinical examination, alveolar bone and inter-implant image performance and post-load repair effect at 6, 12 and 24 months of follow-up were used as evaluation indicators.
RESULTS AND CONCLUSION: (1) In 134 implants, failure was in 2 cases due to surrounding tissue infection. The success rate of before implant restoration was 98.51%, and the success rate after repair was 100%. (2) The stability of dentition of 19 patients was good, showing good occlusion. No mechanical complications or biological complications occurred. The stability of the restoration was 100%. (3) The vertical absorption of bone tissue around all implants was less than 0.2 mm at 6, 12, 24 months after repair, suggesting that the implant has no obvious edge bone resorption. The gingival tissues around all implants were healthy, and no unhealed inflammation or hyperkeratosis appeared. (4) These results imply that the Mis Seven system in the dentition defect fixation exhibits good short-term clinical results.

Key words: Prosthodontics, Dental Implants, Tissue Engineering

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