中国组织工程研究

中国组织工程研究 ›› 2019, Vol. 23 ›› Issue (10): 1496-1500.doi: 10.3969/j.issn.2095-4344.1616

• 组织工程口腔材料 tissue-engineered oral materials • 上一篇    下一篇

树脂材料SureFil SDR行预防性树脂充填的细菌黏附性

徐群昊1，陆钰璞2，白宇宏1   

  1. 1华北理工大学博创口腔医院特需诊室，河北省唐山市 063300；2华北理工大学口腔医学院，河北省唐山市 063300
  • 收稿日期:2018-12-02 出版日期:2019-04-08 发布日期:2019-04-08
  • 通讯作者: 白宇宏，副主任医师，华北理工大学博创口腔医院特需诊室，河北省唐山市 063300
  • 作者简介:徐群昊，女，1992年生，吉林省四平市人，满族，华北理工大学在读硕士，主要从事口腔临床研究。
  • 基金资助:

    国家级大学生创新创业训练项目(201710081032)，项目负责人：陆钰璞

Bacterial adhesion of SureFil SDR as a preventive resin filling

Xu Qunhao1, Lu Yupu2, Bai Yuhong1   

  1. 1VIP Clinic, Bochuang Hospital of Stomatology, North China University of Science and Technology, Tangshan 063300, Hebei Province, China; 2College of Stomatology, North China University of Science and Technology, Tangshan 063300, Hebei Province, China
  • Received:2018-12-02 Online:2019-04-08 Published:2019-04-08
  • Contact: Bai Yuhong, Associate chief physician, VIP Clinic, Bochuang Hospital of Stomatology, North China University of Science and Technology, Tangshan 063300, Hebei Province, China
  • About author:Xu Qunhao, Master candidate, VIP Clinic, Bochuang Hospital of Stomatology, North China University of Science and Technology, Tangshan 063300, Hebei Province, China
  • Supported by:

    the National Students’ Innovation and Entrepreneurship Training Program of China, No. 201710081032 (to LYP)

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摘要：

文章快速阅读：

 

文题释义：
预防性树脂充填：是预防和治疗窝沟龋的有效方法；窝沟封闭剂是传统预防性树脂充填常用的材料，但其存在边缘封闭效果和机械性能较差等缺点；当采用流动树脂Z350XT作为封闭剂时，其抑菌性及远期效果优于传统的窝沟封闭剂；实验采用的SureFil SDR，是一种单组分、含氟、光固化、X射线阻射、具有自流平性的大体积充填树脂材料。
细菌黏附：是细菌与机体组织、生物材料表面发生特异性结合。充填材料的细菌黏附可导致继发龋及充填物脱落等，口腔治疗中应选用不易黏附菌斑、性能良好的材料。树脂粗糙度对细菌黏附量的影响最大。研究选取变形链球菌为实验菌种，通过比较窝沟封闭剂、流动树脂Z350XT和新型大体积充填树脂SureFil SDR的细菌黏附量和粗糙度，定量分析粗糙度对细菌黏附量的影响。
 
 
背景：有研究发现将树脂材料SureFil SDR作为衬洞材料时，较其他流动树脂具有更好的洞壁适应性及独有的自动找平特性，但将其用于预防性树脂充填尚未见报道。
目的：比较窝沟封闭剂、Z350XT流体树脂、SureFil SDR树脂材料在粗糙度与细菌黏附上的差异，探讨树脂材料SureFil SDR行预防性树脂充填的可行性。
方法：将窝沟封闭剂、Z350XT流体树脂、SureFil SDR树脂材料分别制备成8 mm×2 mm×2 mm的长方体试件，利用 MarSurf 粗糙度仪测量3种试件的表面粗糙度。将窝沟封闭剂、Z350XT流体树脂、SureFil SDR树脂材料分别制备成8 mm×8 mm×2 mm的圆柱体试件，放入变形链球菌悬液中培养48 h，检测材料表面的细菌黏附量。

结果与结论：①3种材料表面的粗糙度：SureFil SDR树脂材料< Z350XT流体树脂<窝沟封闭剂，组间两两比较差异均有显著性意义(P < 0.05)；②3种材料表面的细菌黏附量：SureFil SDR树脂材料< Z350XT流体树脂<窝沟封闭剂，组间两两比较差异均有显著性意义(P < 0.05)；③对粗糙度和细菌黏附量之间采用关联性分析，粗糙度和细菌黏附量之间具有高度正相关性，即随着材料粗糙度的减小，细菌黏附量减小(r=0.962，P=0.017 6)；④结果表明，相对于窝沟封闭剂和Z350XT流体树脂而言，SureFil SDR是理想的预防性树脂充填封闭材料。

ORCID: 0000-0002-6727-989X(徐群昊)

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

关键词: 口腔材料, 预防性树脂充填, 细菌黏附性, 流体树脂, 树脂充填封闭材料

Abstract:

BACKGROUND: SureFil SDR as a lining material has better adaptability and unique automatic leveling characteristics as compared with other flowing resins, but its application in preventive resin filling has not been reported.

OBJECTIVE: To compare the roughness and bacterial adhesion among pit and fissure sealant, Z350XT fluid resin and SureFil SDR resin, and to explore the feasibility of preventive resin filling with SureFil SDR resin.
METHODS: Pit and fissure sealant, Z350XT fluid resin and SureFil SDR resin were prepared into 8 mm×2 mm×2 mm cuboid specimens respectively. The surface roughness of the three specimens was measured by MarSurf roughness meter. Pit and fissure sealant, Z350XT fluid resin and SureFil SDR resin were prepared into 8 mm×8 mm×2 mm cylinder specimens respectively. The specimens were cultured in Streptococcus mutans suspension for 48 hours to detect the bacterial adhesion on the material surface.

RESULTS AND CONCLUSION: The roughness of the three materials was ranked as follows: SureFil SDR resin < Z350XT fluid resin < pit and fissure sealant, and there were significant differences between groups (P < 0.05). The bacterial adhesion on the surface of the three materials was ranked as follows: SureFil SDR resin < Z350XT fluid resin < pit and fissure sealant, and there were significant difference between groups (P < 0.05). The correlation between roughness and bacterial adhesion was analyzed, and there was a high positive correlation between roughness and bacterial adhesion, indicating, with the decrease of material roughness, bacterial adhesion decreased (r=0.962, P=0.017 6). The results show that SureFil SDR is an ideal preventive resin filling and sealing material relative to pit and fissure sealant and Z350XT fluid resin.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

Key words: Resins, Synthetic, Bacterial Adhesion, Tissue Engineering

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