中国组织工程研究 ›› 2016, Vol. 20 ›› Issue (51): 7660-7665.doi: 10.3969/j.issn.2095-4344.2016.51.009

• 神经组织构建 nerve tissue construction • 上一篇    下一篇

膈神经与肋间神经移位修复臂丛神经根性撕脱伤

阿不地合比尔•阿不拉1,李  平2,依力哈木江•吾斯曼2,艾合买提江•玉素甫2   

  1. 1新疆维吾尔自治区人民医院小儿外科,新疆维吾尔自治区乌鲁木齐市  830000;2新疆医科大学第一附属医院显微修复重建外科,新疆维吾尔自治区乌鲁木齐市  830000
  • 收稿日期:2016-09-15 出版日期:2016-12-09 发布日期:2016-12-09
  • 通讯作者: 艾合买提江?玉素甫,博士生导师,新疆医科大学第一附属医院显微修复重建外科,新疆维吾尔自治区乌鲁木齐市 830000
  • 作者简介:阿不地合比尔?阿不拉,男,1989年生,新疆维吾尔自治区人,维吾尔族,新疆医科大学第一附属医院在读硕士,主要从事创伤的修复与重建及组织工程的研究。
  • 基金资助:

    国家自然科学基金资助项目(81360270)

Phrenic nerve transfer versus intercostal nerve transfer for the repair of brachial plexus root avulsion injuries

Abdixbir Abra1, Li Ping2, Ilhamjan Usman2, Exmetjan Yüsup2   

  1. 1Department of Pediatrics, the People’s Hospital of Xinjiang Uyghur Autonomous Region, Urumqi 830000, Xinjiang Uyghur Autonomous Region, China; 2Department of Reconstructive Microsurgery, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, Xinjiang Uyghur Autonomous Region, China
  • Received:2016-09-15 Online:2016-12-09 Published:2016-12-09
  • Contact: Exmetjan Yüsup, Doctoral supervisor, Department of Reconstructive Microsurgery, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, Xinjiang Uyghur Autonomous Region, China
  • About author:Abdixbir Abra, Studying for master’s degree, Department of Pediatrics, the People’s Hospital of Xinjiang Uyghur Autonomous Region, Urumqi 830000, Xinjiang Uyghur Autonomous Region, China
  • Supported by:

    the National Natural Science Foundation of China, No. 81360270

摘要:

文章快速阅读:

文题释义:
膈神经移位适用证:①臂丛神经根撕脱伤2年以内,屈肘肌瘫痪,但肌肉萎缩不严重,仍可扪及肌腹;②膈神经功能良好,膈神经最常移位于肌皮神经的运动束。
臂丛神经损伤:臂丛神经由颈C5-8与T1神经根组成,分支主要分布于上肢,有些小分支分布到胸上肢肌、背部浅层肌和颈深肌,主要的分支有:胸背神经、胸长神经、腋神经、肌皮神经、正中神经、桡神经、尺神经。臂丛神经主要支配上肢和肩背、胸部的感觉和运动,臂丛神经损伤后患者上肢功能部分或完全丧失,遗留终生残疾。
摘要
背景:
肋间神经移位和膈神经移位已是治疗肘关节屈曲功能的主要方法,而有些臂丛神经根性撕脱伤患者两种术式均可适用,在这种情况下应该优选哪种修复方式一直是学者们讨论的难题。
目的:观察膈神经移位至臂丛神经上干前股和肋间神经移位至肌皮神经修复臂丛神经根性撕脱伤的疗效。
方法:臂丛神经根性撕脱伤患者20例,其中膈神经移位至臂丛神经上干前股9例(膈神经移位组),肋间神经移位至肌皮神经11例(肋间神经移位组),修复后均获得15-36个月的随访。观察两组患者的切口长度、术中出血量及操作时间并分别进行记录;观察两组患者肱二头肌肌力及肘关节屈曲角度的恢复情况。按中华医学会手外科学会制定的“上肢周围神经功能评定的试用标准”对肌皮神经的功能恢复进行评价,并计算其优良率,评价2种修复方式的治疗效果。
结果与结论:①膈神经移位组优良率为67%,肋间神经移位组优良率为64%,两组优良率对比差异无显著性意义(P > 0.05);②膈神经移位组切口小,出血量少,操作时间短;③膈神经移位组恢复不理想2例,肋间神经移位组恢复不理想3例;④结果表明,2种修复方式对臂丛神经根性撕脱伤患者效果良好,能有效恢复屈肘功能;膈神经移位在切口、出血量及操作时间等方面有优势。

中国组织工程研究杂志出版内容重点:组织构建;骨细胞;软骨细胞;细胞培养;成纤维细胞;血管内皮细胞;骨质疏松组织工程
ORCID: 0000-0002-9830-4576(阿不地合比尔•阿不拉)

关键词: 组织构建, 组织工程, 膈神经, 肋间神经, 神经移位术, 臂丛损伤, 国家自然科学基金

Abstract:

BACKGROUND: Phrenic nerve transfer and intercostal nerve transfer are the accepted surgery strategies for the treatment of brachial plexus root avulsion injuries; however, which surgery is more suitable for the repair remains inconclusive.
OBJECTIVE: To observe the treatment outcomes of brachial plexus root avulsion injuries by transferring the phrenic nerve to the anterior division of the upper trunk of brachial plexus and the intercostal nerve to the musculocutaneous nerve.
METHODS: Twenty patients with brachial plexus root avulsion injuries were included. Among them, 9 were treated with phrenic nerve transfer to the anterior division of the upper trunk of brachial plexus (phrenic nerve transfer group), and 11 were treated with intercostal nerve transfer to the musculocutaneous nerve (intercostal nerve transfer group). Postoperative follow-up ranged from 15 to 36 months. Incision length, blood loss, and operation time were recorded. Muscle strength of the biceps and elbow flexion angle were evaluated. The repair outcome was evaluated by assessing the functional recovery of musculocutaneous nerve according to the criteria issued by the Branch of Hand Surgery of Chinese Medicine Association, and the excellent and good rate was calculated.
RESULTS AND CONCLUSION: The excellent and good rate was 66.7% and 63.6%, respectively, in phrenic nerve transfer group and intercostal nerve transfer group, which is not significantly different between both groups (P > 0.05). Smaller length of operation incision, reduced blood loss, and shorter operation time were found in the phrenic nerve transfer group. Two and three patients in bad recovery were in phrenic nerve transfer and intercostal nerve transfer groups, respectively. These findings suggest that the two kinds of surgery strategies for the repair of brachial plexus root avulsion injuries can obtain good results in the functional recovery of elbow flexion. Phrenic nerve transfer exerts superiorities in operation incision, blood loss and operation time.

中国组织工程研究杂志出版内容重点:组织构建;骨细胞;软骨细胞;细胞培养;成纤维细胞;血管内皮细胞;骨质疏松组织工程

Key words: Phrenic Nerve, Brachial Plexus, Tissue Engineering

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