中国组织工程研究

中国组织工程研究 ›› 2015, Vol. 19 ›› Issue (42): 6764-6769.doi: 10.3969/j.issn.2095-4344.2015.42.008

• 肌肉肌腱韧带组织构建 tissue construction of the muscle, tendon and ligament • 上一篇    下一篇

同种异体肌腱移植重建治疗膝关节前交叉韧带断裂：中期随访评价

贾岩波1，梁子红2，任逸众1，韩长旭1，孔令跃1，额尔敦图1   

  1. 1内蒙古医科大学第二附属医院运动医学科，内蒙古自治区呼和浩特市 010030；2内蒙古自治区人民医院神经内科，内蒙古自治区呼和浩特市 010017
  • 出版日期:2015-10-08 发布日期:2015-10-08
  • 通讯作者: 任逸众，副教授，硕士生导师，内蒙古医科大学第二附属医院运动医学科，内蒙古自治区呼和浩特市 010030
  • 作者简介:贾岩波，男，1983年生，内蒙古自治区呼和浩特市人，满族，2012年内蒙古医科大学毕业，硕士，主治医师，主要从事运动医学的研究。 并列第一作者：梁子红，女，1983年生，内蒙古自治区赤峰市人，汉族，2012年内蒙古医科大学毕业，硕士，主治医师，主要从事神经内科的研究。
  • 基金资助:

    国家自然科学基金资助项目(31260230)；内蒙古医科大学青年创新基金项目(YKD2013QNCX030)；内蒙古自然科学基金项目(2015MS0895)

     

Reconstruction of anterior cruciate ligament with allogeneic tendon: a medium-term follow-up

Jia Yan-bo1, Liang Zi-hong2, Ren Yi-zhong1, Han Chang-xu1, Kong Ling-yue1, Eerduntu1   

  1. 1Department of Arthroscope and Sports Medicine, Second Hospital of Inner Mongolia Medical University, Hohhot 010030, Inner Mongolia Autonomous Region, China; 
    2Department of Internal Neurology, Inner Mongolia People’s Hospital, Hohhot 010017, Inner Mongolia Autonomous Region, China
  • Online:2015-10-08 Published:2015-10-08
  • Contact: Ren Yi-zhong, Associate professor, Master’s supervisor, Department of Arthroscope and Sports Medicine, Second Hospital of Inner Mongolia Medical University, Hohhot 010030, Inner Mongolia Autonomous Region, China
  • About author:Jia Yan-bo, Master, Attending physician, Department of Arthroscope and Sports Medicine, Second Hospital of Inner Mongolia Medical University, Hohhot 010030, Inner Mongolia Autonomous Region, China Liang Zi-hong, Master, Attending physician, Department of Internal Neurology, Inner Mongolia People’s Hospital, Hohhot 010017, Inner Mongolia Autonomous Region, China Jia Yan-bo and Liang Zi-hong contributed equally to this work.
  • Supported by:

    the National Natural Science Foundation of China, No. 31260230; the Natural Science Foundation of Inner Mongolia Autonomous Region, No. 2015MS0895; the Youth Innovation Foundation of Inner Mongolia Medical University, No. YKD2013QNCX030

PDF

320

摘要：

背景：以同种异体肌腱移植重建前交叉韧带是现在较流行的手术方式，但缺乏中长期临床疗效的评价。
目的：分析膝关节镜下同种异体胫前肌腱移植重建前交叉韧带的方法及其中期疗效。
方法：回顾分析应用同种异体肌腱移植重建前交叉韧带的25例患者的临床资料，比较移植前及移植后3年以上的中期随访 Lysholm、Tegner、IKDC关节评分。
结果与结论：所有病例均获得随访。25例患者同种异体肌腱移植后Lysholm关节评分、Tegner评分和IKDC评分均显著高于移植前(均P < 0.05)。所有病例移植后均未出现肺栓塞、感染、移植物断裂等并发症。关节功能明显改善。1例前抽屉试验弱阳性。Lachman试验征均为阴性，轴移试验均阴性。结果表明，关节镜下应用同种异体肌腱移植重建前交叉韧带具有创伤小，并发症少的优势，中期随访疗效优良。
中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

关键词: 组织构建, 组织工程, 肌腱, 前交叉韧带, 同种异体移植, 关节镜, 国家自然科学基金

Abstract:

BACKGROUND: Allogeneic tendon has been frequently used to reconstruct the anterior cruciate ligament. However, there is a lack of middle- and long-term clinical evaluation.

OBJECTIVE: To evaluate the middle- and long-term curative effect of allogeneic tendon reconstruction of the anterior cruciate ligament under arthroscopy．
METHODS: Twenty-five patients with anterior cruciate ligament injury under allogeneic tendon transplantation were reviewed retrospectively. They were all followed up for 3 years or more. The clinical outcomes were evaluated and compared using Lyshlom score scale, IKDC2000 and Tegner score scale.

RESULTS AND CONCLUSION: All the patients were followed up. Lysholm scale scores on the knee function, Tegner scores and IKDC scores were significantly increased after transplantation (P < 0.05). No complications of infection and compartment syndrome occurred. Symptoms were relieved and the function of knee joint was improved. There was one case weakly positive for anterior drawer test. Both Lachman test and pivot shift test showed negative signs. Overall, the reconstruction of anterior cruciate ligament with allogeneic tendon has less trauma and complications, with good middle-term efficacy．
中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

Key words: Anterior Cruciate Ligament, Tendons, Transplantation, Homologous, Tissue Engineering