中国组织工程研究

中国组织工程研究 ›› 2015, Vol. 19 ›› Issue (11): 1727-1731.doi: 10.3969/j.issn.2095-4344.2015.11.017

• 肌肉肌腱韧带组织构建 tissue construction of the muscle, tendon and ligament • 上一篇    下一篇

保留残端同种异体肌腱重建前交叉韧带：更早恢复患膝关节稳定性及运动功能

吴贵佑1，章亚东2，汪喜顺2，侯军虎1，顾东强2   

  1. 1解放军第四军医大学研究生院，陕西省西安市 710032；2解放军总医院第一附属医院骨科研究所，北京市 100048
  • 修回日期:2015-02-13 出版日期:2015-03-12 发布日期:2015-03-12
  • 通讯作者: 章亚东，博士，教授，硕士生导师，解放军总医院第一附属医院骨科研究所，北京市 100048
  • 作者简介:吴贵佑，男， 1985年生，甘肃省靖远县人，汉族，解放军第四军医大学在读硕士，主要从事关节与运动医学临床与基础研究。

Anterior cruciate ligament reconstruction using allogeneic tendon with stump retention under arthroscopy: it is better for the early recovery of knee joint stability and motor function

Wu Gui-you1, Zhang Ya-dong2, Wang Xi-shun2, Hou Jun-hu1, Gu Dong-qiang2   

  1. 1School of Graduate, Fourth Military Medical University of Chinese PLA, Xi’an 710032, Shaanxi Province, China; 2Institute of Orthopedics, First Affiliated Hospital of General Hospital of Chinese PLA, Beijing 100048, China
  • Revised:2015-02-13 Online:2015-03-12 Published:2015-03-12
  • Contact: Zhang Ya-dong, M.D., Professor, Master’s supervisor, Institute of Orthopedics, First Affiliated Hospital of General Hospital of Chinese PLA, Beijing 100048, China
  • About author:Wu Gui-you, Studying for master’s degree, School of Graduate, Fourth Military Medical University of Chinese PLA, Xi’an 710032, Shaanxi Province, China

PDF

581

摘要：

背景：关节镜下重建已成为治疗前交叉韧带损伤的主要治疗手段，在重建时究竟是保留残端疗效好还是清除残端疗效好，目前尚有争议。

目的：探讨关节镜下保留残端应用同种异体肌腱移植重建前交叉韧带的近期临床疗效。
方法：韧带残端存留的前交叉韧带损伤患者75例，随机分成2组：保留残端组38例行关节镜下保留残端前交叉韧带重建；清除残端组37例行清除残端前交叉韧带重建。两组患者全部应用同种异体肌腱移植，移植后3，6，12，24个月随访，分别进行客观稳定性评估(Lachman试验、轴移试验)、膝关节功能评分(IKDC-2000和Lysholm及Tegner评分)。
结果与结论：两组75例患者随访时间均为24个月。Lachman试验、轴移试验两组全部为阴性，在膝关节稳定性方面两组表现无明显差异；保留残端组患者移植后3，6个月IKDC-2000评分显著高于清除残端组(P < 0.05)，保留残端组患者移植后3，6个月时Lysholm及Tegner评分明显高于清除残端组(P < 0.05)，而移植后12，24个月IKDC-2000评分、Lysholm及Tegner评分结果两组差异不明显(P > 0.05)。结果说明关节镜下保留残端重建膝关节前交叉韧带能更早的恢复患者膝关节的稳定性及运动能力，近期疗效优于清除残端重建。


中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程


全文链接：

关键词: 组织构建, 组织工程, 前交叉韧带重建, 保留残端, 同种异体肌腱, 膝关节功能

Abstract:

BACKGROUND: Revascularization under arthroscopy has become the main treatment for anterior cruciate ligament injury, but whether stump retention or removal is better during the reconstruction is still controversial.

OBJECTIVE: To investigate the short-term clinical efficacy of arthroscopic anterior cruciate ligament reconstruction using allogeneic tendon with stump retention.
METHODS: Seventy-five patients with anterior cruciate ligament injury were selected and randomly divided into two groups: stump retention group (n=38 cases) undergoing arthroscopic anterior cruciate ligament reconstruction with stump retention, and control group (n=37) undergoing arthroscopic anterior cruciate ligament reconstruction without stump retention. Both two groups were subject to allogeneic tendon transplantation. At 3, 6, 12, 24 months after transplantation, objective stability assessment (Lachman test, pivot shift test) and knee functional scoring (IKDC-200, Lysholm, Tegner scores) were evaluated.
RESULTS AND CONCLUSION: Both two groups were followed for 24 hours. Lachman test and pivot shift test were negative in the two groups, showing there was no difference in the knee joint stability performance between the two groups. Compared with the control group, the IKDC-200, Lysholm and Tegner scores in the stump retention group were significantly higher at 3, 6 months after transplantaiton (P < 0.05); but there was no difference in these scores between the two groups at 12 and 24 months after transplantation. These findings indicate that arthroscopic anterior cruciate ligament reconstruction with stump retention contributes to earlier recovery of knee joint stability and athletic ability, and has better short-term efficacy than anterior cruciate ligament reconstruction without stump retention.


中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程


全文链接：

Key words: Anterior Cruciate Ligament, Tendons, Transplantation

中图分类号: