中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (16): 3017-3019.doi: 10.3969/j.issn.1673-8225.2011.16.040

• 生物材料临床实践 clinical practice of biomaterials • 上一篇    下一篇

不同类型补片修补腹股沟疝的析因分析

张炜宇   

  1. 东南大学附属中大医院普外二科，江苏省南京市     210009
  • 收稿日期:2010-10-19 修回日期:2011-03-20 出版日期:2011-04-16 发布日期:2011-04-16
  • 作者简介:张炜宇，男，1980年生，江苏省南通市人，汉族，2003年南京医科大学毕业，医师，主要从事普外科研究工作。 zhangwy10@139.com

Factorial analysis of different meshes for repair of inguinal hernia

Zhang Wei-yu   

  1. Second Department of General Surgery, Zhongda Hospital, Southest University, Nanjing  210009, Jiangsu Province, China
  • Received:2010-10-19 Revised:2011-03-20 Online:2011-04-16 Published:2011-04-16
  • About author:Zhang Wei-yu, Physician, Second Department of General Surgery, Zhongda Hospital, Southest University, Nanjing 210009, Jiangsu Province, China zhangwy10@139.com

PDF

419

被引次数

9

摘要：

背景：目前疝修补片的种类较多，包括不可吸收疝修补材料、可吸收疝修补材料、复合型疝修补材料等，为能针对患者的实际情况选用恰当的疝修补材料，需要医生熟悉并掌握各种生物材料的特点。
目的：根据本院病例进行析因分析，评测不同材料在腹外疝修补中的应用效果，旨在了解各种疝修复材料的性能，实现个体化治疗的原则。
方法：以补片种类、腹外疝种类为考察因素，选择聚丙烯、膨体聚四氟乙烯和脱细胞真皮基质片3种补片，腹外疝种类为常见的腹股沟斜疝和腹股沟直疝，利用析因试验设计方法，按照2×3型析因实验设计行不同治疗方案，以平均手术时间、复发率、修补并发症为指标，利用SPSS 10.0统计软件进行析因分析。
结果与结论：以平均手术时间、修补并发症发生率为指标，脱细胞真皮基质片、聚丙烯补片和膨体聚四氟乙烯补片的差异有显著性意义(P< 0.05)，不同腹外疝类型差异无显著性意义(P > 0.05)。由于不同疝种类患者的住院时间差异无显著性意义，那么医生在选用合适疝修补材料时，主要考虑疝修补材料的特性以及患者的临床特点等因素，从而获得最佳临床修补效果。

关键词: 腹股沟疝, 生物材料, 无张力疝修补, 生物相容性, 析因设计

Abstract:

BACKGROUND: At present, there are many kinds of surgical meshes, including nonabsorbable materials, absorbable materials, and composite materials. In order to choose the optimal mesh for patients with inguinal hernia, a physician need to be familiar with characteristics of various biomaterials.
OBJECTIVE: To evaluate the effect of different mesh materials on inguinal hernia in order to master properties of various mesh materials for individual treatment.
METHODS: There were two investigated factors: hernia type and mesh materials. The mesh materials included polypropylene (PP), EPTFE, and acellular dermal matrix tablets. The hernia types were inguinal hernia and direct inguinal hernia. The experiment design was according to 2 × 3 factorial experimental design, and the indexes were average operation time, recurrence rate, and surgical complications. Statistical analysis was done by SPSS 10.0 software.
RESULTS AND CONCLUSION: There were significant differences among PP, EPTFE, and acellular dermal matrix tablets based on the indicators of average operation time and complication incidence (P< 0.05); however, no difference occurred between inguinal hernia and direct inguinal hernia (P > 0.05). These findings indicated that material properties and patients’ manifestations are the key factors to the selection of mesh materials.

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