中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (16): 2980-2984.doi: 10.3969/j.issn.1673-8225.2011.16.031

• 生物材料学术探讨 biomaterial academic discussion • 上一篇    下一篇

人工股骨头材料学特点与临床应用

李  里   

  1. 解放军沈阳军区第二○二医院，辽宁省沈阳市  110003
  • 收稿日期:2011-01-11 修回日期:2011-03-01 出版日期:2011-04-16 发布日期:2011-04-16
  • 作者简介:李里，女，1954年生，江苏省泗阳市人，汉族，1973年白求恩医科大学毕业，主任医师，主要从事老年病学的研究。 jelyh2008@163.com

Material characteristics and clinical application of artificial femoral head

Li Li   

  1. The 202 Hospital of Shenyang Military Area Command of Chinese PLA, Shenyang  110003 Liaoning Province, China
  • Received:2011-01-11 Revised:2011-03-01 Online:2011-04-16 Published:2011-04-16
  • About author:Li Li, Chief Physician, The 202 Hospital of Shenyang Military Area Command of Chinese PLA, Shenyang 110003 Liaoning Province, China jelyh2008@163.com

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371

被引次数

4

摘要：

背景：目前人工股骨头生物材料学的研究已经取得了显著的成果，但仍存在一些问题。
目的：探讨人工股骨头材料学特点与临床应用的研究进展。
方法：应用计算机检索维普数据库，在标题和摘要中以“人工股骨头，研究进展，临床应用”为检索词进行检索。选择文章内容与股骨假体置入后的生物力学相关，同一领域文献则选择近期发表或发表在权威杂志文章，根据纳入标准选择18篇文献进行综述。
结果与结论：人工关节用于临床已有近百年的历史，经科研工作者们的不断努力，人工关节从材料到设计，都取得了很大的进步。多种人工骨置入材料不仅具有合适的孔隙结构、表面形貌和理化性能，良好的生物相容性，同时符合材料的细胞毒性要求，有望成为理想的骨科植入体。但是随着研究的深入，复合材料研究的不断发展，人工骨材料生产工艺的提高，学科工作者将获得结构和性质类似于人体组织具有多种生物活性的生物医学材料，为人工骨修复材料和人工假体的开发及骨缺损修复的治疗带来新的希望。

关键词: 人工股骨头, 生物材料, 转子间骨折, 生物相容性, 综述文献

Abstract:

BACKGROUND: The current studies on biomaterial science of artificial femoral head have obtained remarkable results, but there are still some problems.
OBJECTIVE: To investigate the progress in material characteristics and application of artificial femoral head.
METHODS: A computer search of VIP database was done for articles about biomechanics of artificial femoral head with the keywords of “artificial femoral head, progress, clinical application”. Articles published recently or in authorized journals were preferred. Finally, 18 articles were included.
RESULTS AND CONCLUSION: Artificial joints used in clinic has a history of nearly a hundred years, and the relevant studies about materials and designs have made a great progress. A variety of artificial bone materials are expected to become the ideal orthopedic implants because of their appropriate pore structure, surface morphology, physical and chemical properties, good biocompatibility and cytotoxicity requirements. With the development of composite materials and improvement of production process, various biomedical materials with biological activity which have similar structure and properties to human tissues have been obtained as bone substitute materials, which brings a new hope for the development of artificial prostheses and treatment of bone defects.

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