中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (41): 7761-7764.doi: 10.3969/j.issn.1673-8225.2010.41.039

• 组织构建临床实践 clinical practice in tissue construction • 上一篇    下一篇

青岛地区1 205名汉族青少年骨龄调查

田晓青1，祖玉良2，梁少华1，刘丰春1   

  1. 1青岛大学医学院人体解剖学教研室，山东省青岛市  266071；2青岛市骨伤科医院影像科，山东省青岛市  266021
  • 出版日期:2010-10-08 发布日期:2010-10-08
  • 通讯作者: 刘丰春，教授，青岛大学医学院人体解剖学教研室，山东省青岛市 266071 Liufc2008@yahoo.com.cn
  • 作者简介:田晓青，男，1974年生，山东省青岛市人，汉族，1995年青岛大学医学院毕业，主要从事医学影像诊断研究。 Tian_xq@126.com

Investigation of bone age in 1 205 Han adolescents from Qingdao city

Tian Xiao-qing1, Zu Yu-liang2, Liang Shao-hua1, Liu Feng-chun1   

  1. 1 Department of Human Anatomy, Qingdao University Medical College, Qingdao  266071, Shandong Province, China; 2 Department of Radiology, Qingdao Orthopedics Hospital, Qingdao  266021, Shandong Province, China
  • Online:2010-10-08 Published:2010-10-08
  • Contact: Liu Feng-chun, Professor, Department of Human Anatomy, Qingdao University Medical College, Qingdao 266071, Shandong Province, China Liufc2008@yahoo.com.cn
  • About author:Liu Feng-chun, Professor, Department of Human Anatomy, Qingdao University Medical College, Qingdao 266071, Shandong Province, China Liufc2008@yahoo.com.cn

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摘要：

背景：骨龄为人类生长发育的重要参考指标，国内现引用的数据多为20世纪60年代的统计结果，而对现代青少年骨龄的研究较少。
目的：了解青岛地区汉族青少年膝部和踝部长骨发育状况，探讨骨骺融合的变化趋势，为该地区新的青少年骨龄评价标准积累资料。
方法：随机选择青岛地区9~20岁健康汉族青少年1 205名，拍摄膝部和踝部正位片，统计各长骨干骺融合时间和女生月经初潮情况，并将长骨干骺融合时间与女生月经初潮情况进行相关分析。
结果与结论：膝部及踝部长骨干骺融合时间顺序为：胫骨下端(男生：15.179岁，女生：13.379岁)、腓骨下端(男生：15.290岁，女生：13.472岁)、股骨下端(男生：15.629岁，女生：13.722岁)、腓骨上端(男生：15.708岁，女生：13.753岁)、胫骨上端(男16.329岁，女生：14.027岁)。干骺融合时间男生明显晚于女生。女生月经初潮时间与干骺融合时间成高度正相关。结果表明青岛地区汉族青少年的骨发育有明显提前趋势，因此有必要制定新的反映青少年骨发育水平的骨龄标准。

关键词: 骨龄, 青少年, 干骺融合, 月经初潮, 生长发育, 青岛

Abstract:

BACKGROUND: Bone age is an important reference of growth and development of human race. The data referred to in China was studied in early 1960s, there are few studies concerning modern adolescents.
OBJECTIVE: To assess the long bones’ development in knee and ankle joints of adolescents in Qingdao region, and to investigate the tendency of their skeletal development, which can add new data for the new standard of bone age of adolescents. 
METHODS: Totally 1 205 healthy adolescents, aged 9-20 years, living in Qingdao region were randomly selected. Anterior-posterior radiograms of knees and ankles were obtained. The time of epiphysis-diaphysis fusion of the long bones were observed. Meanwhile the correlation between the menarche and the epiphysis-diaphysis fusion time were analyzed. 
RESULTS AND CONCLUSION: The sequence of the epiphysis-diaphysis fusion in the knee and ankle long bones was as follow: the inferior end of tibia (Male: 15.179 years; Female: 13.379 years), the inferior end of fibula (Male: 15.290 years; Female: 13.472 years), the inferior end of femur (Male: 15.629 years; Female: 13.722 years), the superior end of fibula (Male: 15.708 years; Female: 13.753 years), and the superior end of tibia (Male: 16.329 years; Female: 14.027 years). The females’ menarche was obviously advanced and was highly correlated with the epiphysis-diaphysis time. The bone age of adolescents in Qingdao region is obvious earlier than the old data. New data should be accumulated for the research of anthropology, clinical and forensic medicine.　

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