中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (28): 5289-5292.doi: 10.3969/j.issn.1673-8225.2010.28.038

• 组织构建学术探讨 tissue construction academic discussion • 上一篇    下一篇

骨骼肌肌球蛋白重链与不同类型训练的影响

鲁建清1，汤长发2，尹丽琴2   

  1. 1 湘南学院，湖南省郴州市 423000；2湖南师范大学，湖南省长沙市  410081
  • 出版日期:2010-07-09 发布日期:2010-07-09
  • 通讯作者: 汤长发，博士，教授，湖南师范大学，湖南省长沙市 410081
  • 作者简介:鲁建清，男，1964年生，湖南省沅江市人，汉族，1985年湖南师范大学毕业，副教授，主要从事体育教学与训练方面的研究。 Ljq620308@163.com

Effects of training on myosin heavy chain of skeletal muscles 

Lu Jian-qing1, Tang Chang-fa2, Yin Li-qin2   

  1. 1 Xiangnan University, Chenzhou  423000, Hunan Province, China; 2 Hunan Normal University, Changsha  410081, Hunan Province, China
  • Online:2010-07-09 Published:2010-07-09
  • Contact: Tang Chang-fa, Doctor, Professor, Hunan Normal University, Changsha 410081, Hunan Province, China
  • About author:Lu Jian-qing, Associate professor, Xiangnan University, Chenzhou 423000, Hunan Province, China Ljq620308@163.com

PDF

1138

被引次数

6

摘要：

背景：研究表明，快肌和慢肌的最大缩短速度存在差异, 这主要由于快慢肌所表达的MHC类型不同，引起肌球蛋白ATPase 活性差异的缘故。
目的：介绍不同运动条件下骨骼肌纤维肌球蛋白重链组成变化的研究内容，理解运动训练与骨骼肌收缩性能的关系。
方法：应用计算机检索PubMed与Medline springlink数据库1990-01/2009-10有关骨骼肌肌球蛋白重链的文章，检索词为“skeletal muscle”、“myosin heavy chain”、“training”，限定语言种类为English。同时计算机检索中国期刊全文数据库2000-01/2009-10期间的相关文章，检索词为“骨骼肌，肌球蛋白重链，训练”，限定文章语言种类为中文。纳入标准：不同运动形式对骨骼肌肌球蛋白重链的影响。排除标准：重复或类似的同一研究。
结果与结论：肌球蛋白的形态学特征：快慢肌中含有不同类型肌球蛋白重链。运动对肌球蛋白重链的影响：耐力训练可引起肌球蛋白重链由快向慢转变，但受训练时间、强度以及年龄因素的影响；抗阻力量训练使得快型肌球蛋白重链升高，同时也受训练强度、时程的影响；减少活动大多会引起慢型肌球蛋白重链向快型肌球蛋白重链转化。抗阻力量训练可引起骨骼肌肥大表现为肌纤维肌球蛋白重链增多，以及肌纤维的转化表现为MHC-Ⅱx(以前称Ⅱb MHC)向MHC-Ⅱa转化，低氧训练可以引起慢型肌球蛋白重链向快型方向转化，减少活动方式多数会引起慢型肌球蛋白重链向快型肌球蛋白重链方向转化。

关键词: 肌球蛋白, 肌球蛋白重链, 训练, 运动, 综述文献, 肌肉肌腱组织工程

Abstract:

BACKGROUND: Studies showed that maximum shortening velocity of fast and slow muscle are different, mainly because the different myosin heavy chain types, which are expressed by fast and slow muscle, and cause differences in myosin ATPase activity.
OBJECTIVE: To introduce the composition changes of skeletal muscle fibers and myosin heavy chain under different exercises conditions, and to have a deeply understanding of the relationship between exercises training and skeletal muscle contractility.
METHODS: PubMed and Medline springlink database from January 1990 to October 2009 were searched by computer for articles about the skeletal muscle and myosin heavy chain, with the key words of the “skeletal muscle”, “myosin heavy chain”, and “training”, the language was limited to English. Simultaneously, Chinese Journal Full-text database was searched for the articles during the period of January 2000 to October 2009, the key words were “skeletal muscle, myosin heavy chain, and training,” with the language limited to Chinese. Inclusion criteria: the effect of different forms of exercise on skeletal muscle and myosin heavy chain. Exclusion criteria: repeated or similar studies.
RESULTS AND CONCLUSION: The morphological characteristics of myosin: fast and slow muscles contain different types of myosin heavy chain. The effects of exercises on myosin heavy chain are: endurance training can cause muscle myosin heavy chain transformed from the fast to the slow type, which is affected by training time, intensity and age factors; anti-resistance training can enhance fast myosin heavy chain, which at the same time affected by training intensity, and time duration as well; and reduction of exercises mostly will lead to slow myosin heavy chain transformed to the fast type. And resistance strength training can cause skeletal muscle hypertrophied which is showed as muscle fiber myosin heavy chain increased, and muscle fiber transformation expressed as the myosin heavy chain-Ⅱ x (formerly named Ⅱ b myosin heavy chain) transforms to the myosin heavy chain-Ⅱ, and hypoxia training can lead to slow myosin heavy chain transformed to the fast type, while reduction of exercises mostly will lead to slow myosin heavy chain transformed to fast type too.

中图分类号: