中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (20): 3776-3779.doi: 10.3969/j.issn.1673-8225.2010.20.039

• 组织构建学术探讨 tissue construction academic discussion • 上一篇    下一篇

广州地区中老年人症状性颈椎骨关节炎流行病学调查

苏 阳1，朱志刚2，蔡裕兴3，张忠民1，薛庆云4   

  1. 1南方医科大学第三附属医院骨科，广东省广州市510630；
    南方医科大学南方医院，2脊柱骨病外科， 3放射科，广东省广州市 510515；
    4 卫生部北京医院骨科，北京市  100730
  • 出版日期:2010-05-14 发布日期:2010-05-14
  • 通讯作者: 朱志刚，博士，副主任医师，南方医科大学南方医院脊柱骨病外科，广东省广州市 510515 zzgnfyy@fimmu.com
  • 作者简介:苏 阳，男，1984年生，河北省邢台市人，汉族，南方医科大学在读硕士，主要从事脊柱外科方面的研究。

Epidemiological survey of symptomatic cervical spine osteoarthritis in middle-aged and senior residents in Guangzhou

Su Yang1, Zhu Zhi-gang2, Cai Yu-xing3, Zhang Zhong-min1, Xue Qing-yun4   

  1. 1Department of Orthopaedics, Third Hospital, Southern Medical University, Guangzhou  510630, Guangdong Province, China;
    2Department of Spine and Bone Disease Surgery, 3Department of Radiology, Nanfang Hospital, Southern Medical University, Guangzhou  510515, Guangdong Province, China; 4Department of Orthopaedics, Beijing Hospital,  Ministry of Health of China, Beijing  100730, China
  • Online:2010-05-14 Published:2010-05-14
  • Contact: Zhu Zhi-gang, Doctor, Associate chief physician, Department of Spine and Bone Disease Surgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China zzgnfyy@fimmu.com
  • About author:Su Yang, Studying for master’s degree, Department of Spine Surgery, Third Hospital, Southern Medical University, Guangzhou 510630, Guangdong Province, China
  • Supported by:

    the National Foundation for Science and Technology Research Project during the Eleventh Five-year Plan Period, No. 2006BAI02B02*

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摘要：

背景：颈椎骨关节炎是使颈椎发生障碍的疾病，严重影响中老年人的生活质量，目前国内研究相对较少。
目的：了解广州地区中老年人症状性颈椎骨关节炎患病率。
方法：抽取广州地区具有当地正式户口的40岁及以上居民进行颈椎骨关节炎的流行病学问卷调查。对有症状者进行X射线投照，摄取颈椎正侧位片。颈椎骨关节炎的最终诊断为最严重节段有颈椎骨关节炎临床症状合并影像学Kellgren & Lawrence分级Ⅱ级及以上者。
结果与结论：共分析1 342名40岁以上人群资料，症状性颈椎骨关节炎总患病率为23.2%，女性多于男性(30.2% vs. 15.5%，P < 0.001)。颈椎骨关节炎患病率随年龄增长而升高(P < 0.001)；颈5~6节段骨关节炎患病率为21.0%，明显高于周围节段；城市地区患病率明显高于农村地区(P < 0.001)。调查结果说明广州地区症状性颈椎骨关节炎患病率较高，应当引起重视。

关键词: 中年人, 老年人, 颈椎, 骨性关节炎, 流行病学, 调查分析, 骨组织工程

Abstract:

BACKGROUND: Cervical spine osteoarthritis is a kind of disease that affects cervical joint function which seriously influences quality of life of middle-aged and senior patients and is relatively less investigated in domestic.

OBJECTIVE: To understand the distribution of prevalence of symptomatic cervical spine osteoarthritis (SOA) in middle-aged and senior residents in Guangzhou.

METHODS: Residents who had formal residence certification and over 40 years old were selected and received SOA epidemiology investigation. X-ray inspections were conducted in cervical positive and lateral sides at who had symptoms of cervical spine osteoarthritis. The final diagnostic criteria for symptomatic cervical spine osteoarthritis was osteoarthritis symptoms and Kellgren＆Lawrence classification.

RESULTS AND CONCLUSION: Among 1 342 cases, the total incidence of symptomatic cervical spine osteoarthritis in the middle-aged and senior residents was 23.2%. And male incidence and female incidence were 15.5% and 30.2%, respectively, with a significant difference between them (P < 0.001). The incidence of SOA was increased as the age got increased (P < 0.001). The prevalence of SOA in C5-6 was 21.0%, which was much higher than the other spinal level. There was a significant difference in the prevalence of cervical SOA between urban and rural areas (P < 0.001). This suggested that the prevalence of symptomatic cervical SOA was very high in the middle-aged and senior residents in Guangzhou, and we should pay much attention to it.

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