中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (16): 2953-2957.doi: 10.3969/j.issn.1673-8225.2010.16.026

• 生物材料综述 biomaterial review • 上一篇    下一篇

化力学交互作用对热喷涂生物活性涂层组织与性能的影响

梁佳春，王卫泽，轩福贞   

  1. 华东理工大学承压系统安全科学教育部重点实验室，上海市  200237
  • 出版日期:2010-04-16 发布日期:2010-04-16
  • 通讯作者: 王卫泽，博士，副教授，华东理工大学机械与动力工程学院，上海市 2002374 wangwz@ecust.edu.cn
  • 作者简介:梁佳春★，男，1986年生，江苏省南通市人，汉族，华东理工大学在读硕士，主要从事生物涂层方面的研究。
  • 基金资助:

    国家自然科学基金(50805048)；上海市自然科学基金(08ZR1405700)；教育部新教师基金(200802511008)

Effect of interaction of chemo-mechanics on the microstructure and properties of thermal-sprayed bioactive coatings

Liang Jia-chun, Wang Wei-ze, Xuan Fu-zhen   

  1. Key Laboratory of Safety Science of Pressurized System, Ministry of Education, School of Mechanical and Power Engineering, East China University of Science and Technology, Shanghai  200237, China
  • Online:2010-04-16 Published:2010-04-16
  • Contact: Wang Wei-ze, Doctor, Associate professor, Key Laboratory of Safety Science of Pressurized System, Ministry of Education, School of Mechanical and Power Engineering, East China University of Science and Technology, Shanghai 200237, China wangwz@ecust.edu.cn
  • About author:Liang Jia-chun★, Studying for master’s degree, Key Laboratory of Safety Science of Pressurized System, Ministry of Education, School of Mechanical and Power Engineering, East China University of Science and Technology, Shanghai 200237, China
  • Supported by:

    the National Natural Science Foundation of China, No. 50805048*; the Natural Science Foundation of Shanghai, No. 08ZR1405700*; Young Teacher Foundation of Education Ministry of China, No. 200802511008*

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282

被引次数

1

摘要：

背景：生物涂层假体在体内植入，受到复杂的化力学交互作用，临床返修病例随即增多。
目的：总结化力学交互作用对热喷涂生物活性涂层的组织与性能影响方面的研究现状与进展。
方法：应用计算机检索Elsevier数据库1999-01/2009-11的相关文章。检索词“apatite, coating, spraying”，限定文章语言种类为English。同时计算机检索维普数据库1989-01/2009-11的相关文章，检索词“磷灰石，涂层，喷涂”，限定文章语言种类为中文。纳入文章与热喷涂生物活性涂层的化力学作用密切相关的论文。排除重复性研究及与课题相关性较弱的文献。
结果与结论：力学环境对生物活性涂层的溶解有显著作用，拉应力促进溶解而压应力抑制溶解。另外涂层溶解过程中涂层的力学性能同时受到影响，经过模拟体液浸泡后，涂层的力学性能下降。而植入体内后，由于骨组织参与及生物环境的影响，涂层性能有所升高。但目前仅有简单载荷对涂层组织与性能影响方面的研究，亟需进行拉、扭、疲劳等复合载荷与人体特殊化学环境的耦合场作用下，生物活性涂层的组织与性能的变化规律研究，以保障其结构完整性与性能完整性。

关键词: 磷灰石, 涂层, 喷涂, 生物相容性材料, 综述文献

Abstract:

BACKGROUND: With the bio-coated prosthesis implanted in the body by a complex interaction of chemo-mechanics, the cases of clinical revision increased.
OBJECTIVE: To summarize the research progress of effect of interaction of chemo-mechanics on the microstructure and properties of thermal-sprayed bioactive coatings.
METHODS: The relevant articles were retrieved from Elsevier with the key words of “apatite, coating, spraying” in English between January 1999 to November 2009. Meanwhile, the relevant articles were searched from database of Vip Information with the key words of “apatite, coating, spraying” in Chinese between January 1989 to November 2009. The articles that were highly related to the effect of chemo-mechanics on the microstructure and properties of thermal-sprayed bio-coatings were collected. The repetitive researching results and those with weak correlation were excluded.
RESULTS AND CONCLUSION: It was shown that loading affected the dissolution of bio-coatings significantly. Tensile stress promoted the dissolution, while compressive stress inversely. In addition, the mechanical properties decreased after immersion in simulation body fluid. Moreover, the mechanical properties increased when it was implanted in bone tissue. However, there were only investigation of microstructure and properties of bio-coatings under simple loading. The coupling effect of complex loading, such as tension, torsion and fatigue, etc., and the specific chemical environment on the bio-coatings should be studied in order to ensure the integrity of its structure and properties. 

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