中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (16): 2949-2952.doi: 10.3969/j.issn.1673-8225.2010.16.025

• 生物材料综述 biomaterial review • 上一篇    下一篇

盆底重建替代材料生物补片在妇产科临床中的应用特点

赵永红1，胡金萍2   

  1. 1解放军第二五一医院妇产科，河北省张家口市  075000；2河北省张家口北方学院， 河北省张家口市  075000
  • 出版日期:2010-04-16 发布日期:2010-04-16
  • 作者简介:赵永红，女，河北省张家口市人，汉族，1997年承德医学院毕业，副主任护师，主要从事妇产科临床护理研究。 Zhaoyonghong2010@163.com

Clinical characteristics of pelvic reconstruction using biomaterial patch in females

Zhao Yong-hong1, Hu Jin-ping2   

  1. 1 Department of Gynaecology and Obstetrics, the 251 Hospital of Chinese PLA, Zhangjiakou   075000, Hebei Province, China; 2 Hebei North University, Zhangjiakou   075000, Hebei Province, China
  • Online:2010-04-16 Published:2010-04-16
  • About author:Zhao Yong-hong, Associate chief nurse, Department of Gynaecology and Obstetrics, the 251 Hospital of Chinese PLA, Zhangjiakou 075000, Hebei Province, Chin Zhaoyonghong2010@163.com

PDF

1116

被引次数

10

摘要：

背景：近几年，随着大量生物技术替代材料的应用，盆底缺陷修复和重建有了较大进步，替代材料补片是重要的盆底组织替代物，能够替代薄弱受损的盆底筋膜组织，在盆底重建中的应用越来越广泛。
目的：探讨盆底重建生物材料补片在女性盆底重建中应用的可行性、有效性及临床应用价值。
方法：由第一作者检索1990/2008PubMed数据库(http://www.ncbi.nlm.nih.gov/PubMed)及万方数据库(http://www. wanfangdata.com.cn)有关盆底功能障碍、盆底重建以及补片植入物材料应用等方面的文献，英文检索词为“reconstruction of whole pelvic floor，mesh，synthetic mesh implants”，中文检索词为“补片，生物材料补片，替代材料，盆底重建”。排除重复性研究。计算机初检得到54篇文献，根据纳入标准保留17篇进一步归纳总结。
结果与结论：女性盆底障碍性疾病，表现最为突出的是盆腔器官膨出。盆腔脏器膨出是由于盆底支持结构缺陷、损伤及功能障碍所致。传统的手术解决不了根本问题。目前用于盆底修复及重建的替代材料，大致包括生物材料补片、人工合成材料补片两类，其中生物材料补片分为3种：自身替代材料，同种替代材料，异种替代材料。由于它们能替代薄弱受损的盆底筋膜组织，是重要的盆底组织替代材料，在盆底重建中的应用越来越广泛。应用补片进行盆底重建，真正完成解剖结构的恢复从而达到功能的恢复，方法简单，操作容易，不延长手术时间，不增加手术并发症，患者耐受性好，安全可靠，近期疗效明显，远期疗效有待大量的临床实验和进一步观察。对不同脱垂部位患者均行改良全盆底重建是值得推广的临床经验。

关键词: 补片, 生物材料, 盆底重建, 盆底功能障碍, 人工合成材料, 综述文献

Abstract:

BACKGROUND: With wide application of biotechnological substitute materials, pelvic repair and reconstruction develop to a certain degree. Biomaterial patch is a major substitute for repairing injured pelvic fascia tissue, so it is widely used for pelvic reconstruction.
OBJECTIVE: To investigate the feasibility, efficacy, and clinical value of biomaterial patch to pelvic reconstruction in the females.
METHODS: Articles related to pelvic functional disorder, pelvic reconstruction, and application of patch implant were retrieved from PubMed (http://www.ncbi.nlm.nih.gov/PubMed) and (http://www.wanfangdata.com.cn) with the key words of “reconstruction of whole pelvic floor, mesh, synthetic mesh implants” in both Chinese and English between 1990 and 2008. Duplication studies were excluded. A total of 54 articles were initially retrieved, and 17 ones were included in the final analysis.
RESULTS AND CONCLUSION: Pelvic organ prohpse, which was a major symptom of pelvic disorder in the females, caused by defect of pelvic supporting structure, injury, and functional disorder. Traditional operation could not solve fundamental question. At present, substitute materials for pelvic repair and reconstruction mainly include biomaterial patch (self-substitute materials, homogeneity substitute materials, and heterogeneity substitute materials) and artificial patch. All of them could substitute the injured pelvic fascia tissue; therefore, they were major substitute materials of pelvic tissue and widely used for pelvic reconstruction. Patch which was used for pelvic reconstruction realized the recovery of anatomic structure and caused functional recovery, with simple and easy processing. Additionally, patch application did not prolong operative time and cause complication, but induced well tolerance, security and reliability, and remarkable short-term effect on patients. However, the long-term efficacy should be further studied. The modified pelvic reconstruction is clinically valuable for patients with varying prolapsed sites.

中图分类号: