Chinese Journal of Tissue Engineering Research ›› 2018, Vol. 22 ›› Issue (23): 3634-3639.doi: 10.3969/j.issn.2095-4344.0243

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Continuous negative pressure drainage for treating wound infection after posterior lumbar spine cage fusion and pedicle screw fixation  

Xu Zhun, Yan Yi-guo, Wang Cheng, Xue Jing-bo, Wang Ming, Shu Xiao-lin, Wang Wen-jun   

  1. Department of Spine Surgery, The First Affiliated Hospital of University of South China, Hengyang 421001, Hunan Province, China
  • Online:2018-08-18 Published:2018-08-18
  • Contact: Wang Wen-jun, Master’s supervisor, Chief physician, Department of Spine Surgery, The First Affiliated Hospital of University of South China, Hengyang 421001, Hunan Province, China
  • About author:Xu Zhun, Master, Attending physician, Department of Spine Surgery, The First Affiliated Hospital of University of South China, Hengyang 421001, Hunan Province, China
  • Supported by:

    the Scientific Research Project of Health and Family Planning Committee of Hunan Province, No. C20180213, B20180154; the Key Scientific Research Project of Health and Family Planning Committee of Hunan Province, No. A2017016

Abstract:

BACKGROUND: The treatment effect of deep infection of early wound after posterior lumbar fusion is related to the adequacy of wound drainage.

OBJECTIVE: To discuss the effect of continuous negative pressure drainage on early wound deep infection after posterior lumbar spine fusion.
METHODS: Totally 20 patients with deep wound infection in early stage after posterior lumbar spine fusion were treated with debridement and drainage from August 2012 to December 2016, and the conservative treatment was invalid. 10 patients in the conventional drainage group were drained by drainage tube and the other 10 patients in the negative pressure drainage group were drained by drainage tube connected with the continuous negative pressure. The wound healing time and interbody fusion time were compared between the two groups. Before debridement, 3 days and 3 months after surgery, Visual Analogue Scale score was compared, and the results of the microbiological culture were also observed.
RESULTS AND CONCLUSION: (1) All patients in two groups healed after debridement. The wound healing time was significantly faster in the negative pressure drainage group than that in the conventional drainage group (P < 0.05). (2) The interbody fusion time was not significantly different between the conventional drainage group and negative pressure drainage group. (3) Visual Analogue Scale scores were not significantly different between the two groups before surgery and 3 months after surgery. The Visual Analogue Scale scores were significantly lower in the negative pressure drainage group than in the conventional drainage group (P < 0.05). (4) For microbial cultures, the positive results were found in 16 patients and the negative results were found in 4 patients. (5) Results suggested that continuous negative pressure drainage can shorten the time of treating the wound infection after the posterior lumbar spine fusion and relieve the early pain. 

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程

Key words: Prostheses and Implants, Spinal Fusion, Lumbar Vertebrae, Drainage, Tissue Engineering

CLC Number: