Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (12): 1864-1871.doi: 10.3969/j.issn.2095-4344.2015.12.012

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Nano-collagen artificial bone for alveolar ridge preservation in the Kazakh from Xinjiang Tacheng Region

Wang Cheng-yue1, Zhao Yuan2, Yang Man2, Wang Shu-feng3   

  1. 1Department of Prosthodontics, Second Affiliated Hospital of Liaoning Medical University, Jinzhou 121000, Liaoning Province, China
    2School of Graduate, Liaoning Medical University, Jinzhou 121000, Liaoning Province, China
    3Department of Prosthodontics, Stomatology Hospital of Xuzhou City, Xuzhou 221000, Jiangsu Province, China
  • Revised:2015-02-15 Online:2015-03-19 Published:2015-03-19
  • Contact: Wang Cheng-yue, Department of Prosthodontics, Second Affiliated Hospital of Liaoning Medical University, Jinzhou 121000, Liaoning Province, China
  • About author:Wang Cheng-yue, M.D., Associate chief physician, Department of Prosthodontics, Second Affiliated Hospital of Liaoning Medical University, Jinzhou 121000, Liaoning Province, China
  • Supported by:

    the Scientific Research and Technological Development Project in Tacheng Region, No. 2013406

Abstract:

BACKGROUND: It is an important issue of alveolar ridge preservation after tooth extraction. Because of the limited treatment and geographical conditions, lack of awareness of oral health, many local people in frontier areas in Xinjiang have poor alveolar ridge that is not of timely repair after tooth extraction. Thus, it is important to find a suitable local and efficient way to save the residual ridge, which has a more practical clinical value.
OBJECTIVE: To investigate the feasibility of nano-collagen artificial bone used for alveolar ridge preservation in the Kazakh in Xinjiang Tacheng Region, China.
METHODS: Sixty-eight Kazakh patients with bilateral extraction from Tacheng region, Xingjiang Uygur Autonomous Region, China were selected in a self-controlled trial. According to the principle of a minimum allocation imbalance index, the experimental side and control side of extraction patients were confirmed. In the experimental side, nano-collagen artificial bone was implanted; while, conventional treatment was done in the control side. Multi-slice spiral CT was used to scan the regions of extraction interest to measure the relative gray value of alveolar bone mineral density immediately and 3 months after implantation.
RESULTS AND CONCLUSION: Immediately after implantation, tooth extraction sockets were visible on CT images both in the experimental and control sides; but after 3 months, the extraction sockets became unclear on the CT images, and CT values were close to those of the surrounding alveolar process, but bone tissues were full of the bone graft area in the experimental side. The alveolar bone mineral density was higher in the experimental side than the control side at 3 months after implantation. These findings indicate that the nano-collagen artificial bone has good clinical achievement in alveolar ridge preservation in the Kazakh in Xinjiang Tacheng Region.


中国组织工程研究杂志出版内容重点:生物材料;骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性;组织工程


全文链接:

Key words: Collagen, Dental Implants, Bone Density, Alveolar Process

CLC Number: