Morphology of intervertebral disc in Chinese adults evaluated using computer tomography three-dimensional imaging

doi:10.3969/j.issn.2095-4344.0174

Abstract

Abstract:

BACKGROUND: The artificial disc requires a height, a width, and a shape as much as possible to be similar to the original intervertebral disc in order to perfectly distribute the load. At present, most of the data are from foreign countries or measured using X-ray and magnetic resonance imaging, but there are some shortcomings.

OBJECTIVE: To diagnose the spinal disease and provide data for the design of a native lumbar disc device by measuring the normal lumbar intervertebral disc using computer tomography (CT).

METHODS: A total of 2 235 patients who underwent lumbar CT examination in Liuzhou Worker’s Hospital from January 2012 to May 2017 were collected and analyzed. There were 62 cases, including 45 males and 17 females, after being strictly met the inclusion and exclusion criteria. From the age of 20, they were divided into four groups: 20-30, 31-40, 41-50 and more than 50 years old. The range was from L₁ to S₁. The measurement index include intervertebral disc anteroposterior diameter, transerverse diameter, disc volume, sagittal anterior, middle and posterior height, coronal left and right height, and interverterbral angle.

RESULTS AND CONCLUSION: (1) In terms of age, there was a statistically significant difference in measurement indexes between L_1/2, L_2/3 and L_3/4 (P < 0.05). Therefore, the factor of age should be taken into account. However, there was no statistically significant difference between L_4/5and L₅/S₁ segments (P > 0.05). (2) There was a statistical difference between the anterior and middle height of the sagittal position in L_4/5 and L₅/S₁ (P < 0.05). (3) There were statistical differences between the angles of L_2/3, L_3/4, L_4/5, L₅/S₁ intervertebral space (P < 0.05), but the difference of angle between L_4/5 and L₅/S₁ was the most. (4) There was no statistical difference in the height between the left and right sides of the coronal position (P > 0.05). (5) There was statistical difference between the anteroposterior and transverse diameters of the disc on the adjacent cross section (P < 0.05). (6) The results showed that the lower the segment, the smaller the statistical difference between each group. It is indicated that the age difference should be considered on the L_1/2, L_2/3, and L_3/4 segments in the design of lumbar disc or interbody fusion. The lumbar artificial intervertebral disc can be placed in the middle or side. The artificial disc should be designed into the wedge shape instead of a rectangle. These will provide a good anatomical basis for the design of domestic lumbar artificial intervertebral discs.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Lumbar Vertebrae, Intervertebral Disk, Spinal Fusion, Internal Fixators, Tissue Engineering

CLC Number:

R318

Xiao Kan-kan, Li Bing, Peng Xiao-zhong, Zhuo Xiang-long, Xie Chao-xian. Morphology of intervertebral disc in Chinese adults evaluated using computer tomography three-dimensional imaging [J]. Chinese Journal of Tissue Engineering Research, 2018, 22(11): 1749-1755.

Figures/Tables 4

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