Chinese Journal of Tissue Engineering Research ›› 2017, Vol. 21 ›› Issue (22): 3567-3575.doi: 10.3969/j.issn.2095-4344.2017.22.021

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A review on nano-materials as joint replacement implants

Wang Lin1, Chen Dan-ying2, Zhang Zhi-yu1, Zhang Hang-zhou3
  

  1. 1Department of Orthopedics, the 4th Affiliated Hospital of China Medical University, Shenyang 110032, Liaoning Province, China; 2Department of Rehabilitation, Shengjing Hospital of China Medical University, Shenyang 110134, Liaoning Province, China; 3Department of Orthopedics, the 1st Affiliated Hospital of China Medical University, Shenyang 110000, Liaoning Province, China
  • Online:2017-08-08 Published:2017-09-01
  • Contact: Zhang Hang-zhou, M.D., Associate chief physician, Department of Orthopedics, the 1st Affiliated Hospital of China Medical University, Shenyang 110000, Liaoning Province, China
  • About author:Wang Lin, Master, Physician, Department of Orthopedics, the 4th Affiliated Hospital of China Medical University, Shenyang 110032, Liaoning Province, China
  • Supported by:
    the National Natural Science Foundation of China, No. 81671811, 81501857

Abstract:

BACKGROUND: Implant related problems such as loosening, dislocation and infection often come along with joint replacement. Nanotechnology provides a new insight into the preparation of joint replacement implants.
OBJECTIVE: To elaborate the research progress of nanotechnology in improving joint replacement implants.
METHODS: The first author used the computer to retrieve PubMed databases using the key words of “joint replacement, artificial implant, nanotechnology, nano-materials, nanoscales, biocompatibility” in English, to find relevant literature on nanotechnology and joint replacement implants. All data were primarily screened to exclude repeated and irrelevant articles, and finally 51 articles related to the study were retained.
RESULTS AND CONCLUSION: Through reviewing these 51 articles, we make a detailed introduction about some of the biological responses that occur with nano-materials, and some of the biocompatibility problems that have been raised in relation to materials, as well as the ways that have been employed to improve biocompatibility of nano structured materials. But the long-term effect of nanotechnology on the human body is still worthy of further research in medicine or related fields. 

Key words: Tissue Engineering, Biocompatible Materials, Nanotubes

CLC Number: