Bioactive glass effects on remineralization of early artificial enamel caries

doi:10.3969/j.issn.2095-4344.2013.21.010

Abstract

Abstract:

BACKGROUND: Bioactive glass has good biocompatibility and could control oral bacteria and protect against dentin hypersensitivity.
OBJECTIVE: To evaluate remineralization effect of bioactive glass on early artificial enamel caries.
METHODS: Thirty bovine incisors fresh were made to artificial caries models, and were placed in a container with demineralization iquid at 37 ℃ for 72 hours. Micro hardness tester was used to detect hardness value after demineralization, and the enamel surfaces were observed by scanning electron microscope. Then, the samples were randomly divided into three groups, 10 in each group. Using pH cycle way method, the oral environment of human beings was copied. Samples were respectively soaked in bioactive glass solution, sodium fluoride solution and artificial saliva solution, three times a day and 10 minutes each. These three groups were dipped circularly into an artificial cariogenic solution and an artificial saliva solution for 20 days. The scanning electron microscope was used to observe demineralization and remineralization on the enamel surface. Micro hardness tester was employed to detect enamel hardness.
RESULTS AND CONCLUSION: The enamel surface in the experiment group was smoother than the other two control groups. The micro hardness of the experiment group was higher than that of the two control groups (P < 0.05). Therefore, bioactive glass can promote remineralization of early artificial enamel caries in vitro.

Key words: biomaterials, tissue-engineered oral materials, bioactive glass, enamel, early artificial enamel caries, remineralization, artificial demineralization, micro hardness, pH cycle experiment, oral biomaterials, other grants-supported paper

CLC Number:

R318

Wang Yin, Wang Yu, Dong Bo, Zhang Ting, Chen Si-jie, Qu Yuan-yuan. Bioactive glass effects on remineralization of early artificial enamel caries[J]. Chinese Journal of Tissue Engineering Research, doi: 10.3969/j.issn.2095-4344.2013.21.010.

Figures/Tables 3

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