Tendinopathy and the extracellular matrix: to deeply study the key proteins and enzymes in the bone-tendon junction

doi:10.3969/j.issn.2095-4344.2016.15.019

Abstract

Abstract:

BACKGROUND: In recent years, research on tendinopathy is becoming a hot topic in the sports medicine and rehabilitation, and the extracellular matrix plays a considerable role in the occurrence, development and healing of tendinopathy.

OBJECTIVE: To explore the relationship between tendinopathy and the extracellular matrix.

METHODS: CNKI, VIP, CBM, Wanfang, PubMed and Embase were retrieved for articles related to collagen, protein, glycoprotein and matrix remodeling published since 2000.

RESULTS AND CONCLUSION: After tendinopathy, there are obvious changes in collagen, proteoglycans, glycoprotein and related enzymes; and these changes also affect the reconstruction and repair of tendinopathy. Currently, most of researches focus on the tendon rather than the bone-tendon junction. This means that there are no in-depth studies on the correlation between many important proteins and tendinopathy, and the effects of exercise intervention.
中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

Key words: Tendons, Extracellular Matrix, Sports Medicine

Liu Chun-yu, Han Xiao-yan, Wang Lin. Tendinopathy and the extracellular matrix: to deeply study the key proteins and enzymes in the bone-tendon junction[J]. Chinese Journal of Tissue Engineering Research, 2016, 20(15): 2265-2272.

Figures/Tables 4

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